Search International and National Patent Collections
Some content of this application is unavailable at the moment.
If this situation persists, please contact us atFeedback&Contact
1. (WO1997018855) DEVICE FOR ENHANCED DELIVERY OF BIOLOGICALLY ACTIVE SUBSTANCES AND COMPOUNDS IN AN ORGANISM
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1997/018855 International Application No.: PCT/EP1996/005086
Publication Date: 29.05.1997 International Filing Date: 19.11.1996
Chapter 2 Demand Filed: 17.06.1997
IPC:
A61M 37/00 (2006.01) ,A61N 1/30 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
M
DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
37
Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
N
ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
1
Electrotherapy; Circuits therefor
18
Applying electric currents by contact electrodes
20
continuous direct currents
30
Apparatus for iontophoresis or cataphoresis
Applicants:
LERNER, Eduard, Naumovich [NL/NL]; NL
LERNER, Leonid [RU/US]; US (UsOnly)
Inventors:
LERNER, Eduard, Naumovich; NL
LERNER, Leonid; US
Common
Representative:
LERNER, Eduard, Naumovich; A.J. Ernststraat 17 NL-1083 GP Amsterdam, NL
Priority Data:
95203173.021.11.1995EP
95203601.022.12.1995EP
96200081.622.01.1996EP
96200082.422.01.1996EP
Title (EN) DEVICE FOR ENHANCED DELIVERY OF BIOLOGICALLY ACTIVE SUBSTANCES AND COMPOUNDS IN AN ORGANISM
(FR) DISPOSITIF POUR AMELIORER L'ADMINISTRATION A L'ORGANISME DE SUBSTANCES ET DE COMPOSES BIOLOGIQUEMENT ACTIFS
Abstract:
(EN) A device to enhance the delivery of a drug or other substance of interest into a selected organ or tissue, comprising special electrodes, one of the electrodes carrying a container with the selected drug or other substance of interest, said electrodes being capable of being positioned at preselected locations of said organ or tissue, wherein the electrodes are all connected with a selected energy source which generates and maintains an energy field before and during the enhanced delivery of said substance, under the influence of which delivery is accomplished in a direction from the active to the passive electrode and into said organ or tissue. The energy source may be selected from suitable sources providing an electric field, a magnetic field, ultrasonic waves, high energy waves like laser beams, or a combination thereof. Further a method for the enhanced delivery of said drug or other substance of interest to an internal organ or target tissue of an organism, for example the brain, bypassing the blood-brain barrier, is disclosed.
(FR) L'invention concerne un dispositif pour améliorer l'administration d'un médicament ou de toute autre substance souhaitée à un organe ou tissu choisi, comprenant des électrodes spéciales, une de ces électrodes portant un récipient avec le médicament choisi ou une autre substance souhaitée, ces électrodes pouvant être placées à des emplacements prédéterminés de l'organe ou du tissu en question. Ces électrodes sont toutes connectées à une source d'énergie sélectionnée qui produit et entretient un champ d'énergie avant et durant l'administration accrue de cette substance et qui assure le transport de la substance dans la direction depuis l'électrode active vers l'électrode passive et dans l'organe ou le tissu. La source d'énergie peut être choisie de toute manière appropriée et elle peut émettre un champ électrique, un champ magnétique, des ondes ultrasoniques, des ondes haute énergie, telles que des faisceaux laser ou une combinaison de ceux-ci. En outre, l'invention concerne un procédé pour une administration accrue d'un médicament ou d'une autre substance souhaitée vers un organe ou un tissu interne cible d'un organisme, par exemple le cerveau, en court-circuitant la barrière hémato-encéphalique.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, HU, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, TJ, TM, TR, TT, UA, UG, US, UZ, VN
African Regional Intellectual Property Organization (ARIPO) (KE, LS, MW, SD, SZ, UG)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
MXPA/a/1998/004007EP0869829US20020068080US20020082583US20020183683US20020123678
US20030191426US20040064127JP2000500999CN1206353CA2238055AU1996076932