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1. (WO1997018299) IN VITRO CHONDROGENIC INDUCTION OF HUMAN MESENCHYMAL STEM CELLS
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/1997/018299 International Application No.: PCT/US1996/018371
Publication Date: 22.05.1997 International Filing Date: 15.11.1996
Chapter 2 Demand Filed: 19.05.1997
IPC:
A61K 35/30 (2006.01) ,A61L 27/00 (2006.01) ,C12N 5/077 (2010.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35
Medicinal preparations containing material or reaction products thereof with undetermined constitution
12
Materials from mammals or birds
30
Nerves; Brain
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
L
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27
Materials for prostheses or for coating prostheses
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5
Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
07
Animal cells or tissues
071
Vertebrate cells or tissues, e.g. human cells or tissues
077
Mesenchymal cells, e.g. bone cells, cartilage cells, marrow stromal cells, fat cells or muscle cells
Applicants:
CASE WESTERN RESERVE UNIVERSITY [US/US]; 10900 Euclid Avenue Cleveland, OH 44106-7080, US
Inventors:
JOHNSTONE, Brian; US
YOO, Jung; US
Agent:
HERRON, Charles, J. ; Carella, Byrne, Bain, Gilfillan, Cecchi, Stewart & Olstein 6 Becker Farm Road Roseland, NJ 07068, US
Priority Data:
60/006,86616.11.1995US
Title (EN) IN VITRO CHONDROGENIC INDUCTION OF HUMAN MESENCHYMAL STEM CELLS
(FR) INDUCTION IN VITRO DE LA CHRONDROGENESE DES CELLULES SOUCHES MESENCHYMATEUSES HUMAINES
Abstract:
(EN) Disclosed are a composition of chemically defined components which support the $i(in vitro) chondrogenesis of mesenchymal progenitor cells, a method for $i(in vitro) chondrogenic induction of such progenitor cells and a method of forming human chondrocytes $i(in vitro) from such progenitor cells.
(FR) L'invention se rapporte à une composition constituée d'éléments définis chimiquement qui induisent la chondrogenèse $i(in vitro) des cellules reproductrices mésenchymateuses, à un procédé d'induction $i(in vitro) de la chondrogenèse des cellules reproductrices en question et à un procédé d'élaboration $i(in vitro) des chondrocytes à partir desdites cellules reproductrices.
Designated States: AU, CA, JP
European Patent Office (EPO) (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
Publication Language: English (EN)
Filing Language: English (EN)