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1. (WO1997018239) PEPTIDE CONJUGATES DERIVED FROM THYMIC HORMONES, THEIR USE AS MEDICAMENT AND COMPOSITIONS CONTAINING THEM
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1997/018239 International Application No.: PCT/FR1996/001812
Publication Date: 22.05.1997 International Filing Date: 15.11.1996
Chapter 2 Demand Filed: 13.06.1997
IPC:
A61K 38/00 (2006.01) ,C07K 7/06 (2006.01) ,C07K 14/66 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
7
Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
04
Linear peptides containing only normal peptide links
06
having 5 to 11 amino acids
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
575
Hormones
66
Thymopoietins
Applicants:
INSTITUT EUROPEEN DE BIOLOGIE CELLULAIRE [FR/FR]; 18, avenue de l'Europe Villa Missouri - Tech Village 2 F-31520 Ramonville-Saint-Agne, FR (AllExceptUS)
DUSSOURD D'HINTERLAND, Lucien [FR/FR]; FR (UsOnly)
PINEL, Anne-Marie [FR/FR]; FR (UsOnly)
Inventors:
DUSSOURD D'HINTERLAND, Lucien; FR
PINEL, Anne-Marie; FR
Agent:
MARTIN, Jean-Jacques ; Cabinet Regimbeau 26, avenue Kléber F-75116 Paris, FR
Priority Data:
95/1354415.11.1995FR
Title (EN) PEPTIDE CONJUGATES DERIVED FROM THYMIC HORMONES, THEIR USE AS MEDICAMENT AND COMPOSITIONS CONTAINING THEM
(FR) CONJUGUES PEPTIDIQUES DERIVES DES HORMONES THYMIQUES, LEUR UTILISATION A TITRE DE MEDICAMENT ET COMPOSITIONS LES CONTENANT
Abstract:
(EN) The invention relates to peptide conjugates comprising a sequence of at least 3 amino acids derived from a thymic hormone selected amongst thymuline and thymopoïetine, the amino acids being independently in the form D, L or DL, said sequence being chemically or physically conjugated with at least one compound selected amongst monocarboxylic acids having the general formula (I): HOOC-R, as well as alcohol, aldehyde or amide derivatives, the dicarboxylic acids having the general formula (II): HOOC-R1-COOH. The invention also relates to the use of such conjugates as medicaments, and pharmaceutical or cosmetological compositions containing them.
(FR) L'invention concerne des conjugués peptidiques comprenant une séquence d'au moins 3 acides aminés dérivés d'une hormone thymique choisie parmi la thymuline et la thymopoïétine, les acides aminés pouvant être indépendamment sous forme D, L ou DL, ladite séquence étant conjuguée chimiquement ou physiquement avec au moins un composé sélectionné parmi: les acides monocarboxyliques de la formule générale (I): HOOC-R, ainsi que les dérivés alcool, aldéhyde ou amide; les acides dicarboxyliques de la formule générale (II): HOOC-R1-COOH. Elle concerne également leur utilisation à titre de médicament et des compositions pharmaceutiques ou cosmétologiques les contenant.
Designated States: AU, CA, JP, US
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
Publication Language: French (FR)
Filing Language: French (FR)
Also published as:
ES2196187EP0861266US6211155JP2000500447CA2237995DE000069627691
AU1996076832FR2741076