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1. (WO1997018204) SUBSTITUTED TETRAHYDROPYRIDINE DERIVATIVES ACTING ON 5-HT RECEPTORS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1997/018204 International Application No.: PCT/GB1996/002763
Publication Date: 22.05.1997 International Filing Date: 13.11.1996
Chapter 2 Demand Filed: 25.04.1997
IPC:
C07D 401/06 (2006.01) ,C07D 401/14 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
401
Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
02
containing two hetero rings
06
linked by a carbon chain containing only aliphatic carbon atoms
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
401
Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
14
containing three or more hetero rings
Applicants:
MERCK SHARP & DOHME LIMITED [GB/GB]; Hertford Road Hoddesdon Hertfordshire EN11 9BU, GB (AllExceptUS)
BOURRAIN, Sylvie [FR/GB]; GB (UsOnly)
MACLEOD, Angus, Murray [GB/GB]; GB (UsOnly)
SHOWELL, Graham, Andrew [GB/GB]; GB (UsOnly)
Inventors:
BOURRAIN, Sylvie; GB
MACLEOD, Angus, Murray; GB
SHOWELL, Graham, Andrew; GB
Agent:
THOMPSON, John; Merck & Co., Inc. European Patent Dept. Terlings Park, Eastwick Road Harlow Essex CM20 2QR, GB
Priority Data:
9523462.116.11.1995GB
Title (EN) SUBSTITUTED TETRAHYDROPYRIDINE DERIVATIVES ACTING ON 5-HT RECEPTORS
(FR) DERIVES TETRAHYDROPYRIDINE SUBSTITUES AGISSANT SUR LES RECEPTEURS 5-HT
Abstract:
(EN) The present invention provides a compound of formula (I) or a salt or prodrug thereof, wherein E, G, Q, R1, T, U, V and Z are as herein defined, as a selective agonist of '5-HT1-like' receptors, processes for making it, pharmaceutical compositions containing it and its use in therapy.
(FR) L'invention concerne un composé de la formule (I), un sel ou un précurseur de celui-ci. Dans cette formule E, G, Q, R1, T, U, V et Z et Z sont tels que définis dans la description. Ces composés sont des agonistes actifs des récepteurs du type 5-HT1. L'invention concerne également des procédés pour préparer ces composés, des préparations pharmaceutiques les contenant et leur utilisation thérapeutique.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, HU, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, TJ, TM, TR, TT, UA, UG, US, UZ, VN
African Regional Intellectual Property Organization (ARIPO) (KE, LS, MW, SD, SZ, UG)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
US6054469AU1996075783