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1. (WO1997017974) OCULAR DEPRESSOR
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1997/017974 International Application No.: PCT/JP1996/003351
Publication Date: 22.05.1997 International Filing Date: 14.11.1996
IPC:
C07D 307/93 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
307
Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
77
ortho- or peri-condensed with carbocyclic rings or ring systems
93
condensed with a ring other than six-membered
Applicants:
TORAY INDUSTRIES, INC. [JP/JP]; 2-1, Nihonbashi Muromachi 2-chome Chuo-ku Tokyo 103, JP (AllExceptUS)
KURUMATANI, Hajimu [JP/JP]; JP (UsOnly)
KAWASHIMA, Ayako [JP/JP]; JP (UsOnly)
ISOGAYA, Masafumi [JP/JP]; JP (UsOnly)
WAKITA, Hisanori [JP/JP]; JP (UsOnly)
Inventors:
KURUMATANI, Hajimu; JP
KAWASHIMA, Ayako; JP
ISOGAYA, Masafumi; JP
WAKITA, Hisanori; JP
Priority Data:
7/29578914.11.1995JP
Title (EN) OCULAR DEPRESSOR
(FR) DEPRESSEUR OCULAIRE
Abstract:
(EN) An ocular depressor containing as the active ingredient 4,8-inter-m-phenylene PGI2 derivatives typified by compounds represented by general formula (I), in particular, formula (II), or pharmacologically acceptable salts thereof. The drug is useful as a remedy for a number of states with high ocular tension such as glaucoma, ocular hypertension and postoperative high ocular tension.
(FR) La présente invention concerne un dépresseur oculaire dont l'ingrédient actif est constitué par des dérivés de 4,8-inter-m-phénylène PGI2 dont le type est obtenu au moyen de composés représentés par la formule générale (I), en particulier la formule (II), ou de sels de ces composés acceptables en pharmacie. Ce médicament est utile comme remède pour un certain nombre d'états impliquant une tension oculaire élevée, comme le glaucome, l'hypertension oculaire et la tension oculaire élevée post-opératoire.
Designated States: AU, CA, CN, JP, KR, NO, US
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)
Also published as:
NO19973122EP0795331US6127413CN1177926CA2210255KR1019980701417
AU1996075873