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1. (WO1997017331) SUBSTANTIALLY PURE APRACLONIDINE AND ITS USE IN LOWERING INTRAOCULAR PRESSURE
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1997/017331 International Application No.: PCT/US1996/015392
Publication Date: 15.05.1997 International Filing Date: 26.09.1996
Chapter 2 Demand Filed: 20.05.1997
IPC:
C07D 233/50 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
233
Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
04
having one double bond between ring members or between a ring member and a non-ring member
28
with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
44
Nitrogen atoms not forming part of a nitro radical
50
with carbocyclic radicals directly attached to said nitrogen atoms
Applicants:
ALCON LABORATORIES, INC. [US/US]; 6201 South Freeway Fort Worth, TX 76134-2099, US
Inventors:
YORK, Billie, M.; US
YANNI, John, M.; US
DUPRIEST, Mark, T.; US
Agent:
YEAGER, Sally, S. ; Alcon Laboratories, Inc. Patent Dept., Q-148 6201 South Freeway Fort Worth, TX 76134-2099, US
WAIN, Christopher, Paul ; A.A. Thornton & Co. Northumberland House 303-306 High Holborn London WC1V 7LE, GB
Priority Data:
08/555,25208.11.1995US
Title (EN) SUBSTANTIALLY PURE APRACLONIDINE AND ITS USE IN LOWERING INTRAOCULAR PRESSURE
(FR) APRACLONIDINE SENSIBLEMENT PURE ET SON UTILISATION DANS L'ABAISSEMENT DE LA PRESSION INTRA-OCULAIRE
Abstract:
(EN) The present invention is directed to substantially pure apraclonidine of structure (I), compositions thereof and methods for controlling intraocular pressure.
(FR) Cette invention concerne la production d'apraclonidine sensiblement pure de la structure (I), des compositions la contenant, ainsi que des procédés permettant de régler la pression intra-oculaire.
Designated States: AU, CA, JP, MX
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
AU1996072459