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1. (WO1997016555) ASPERGILLUS NIGER BETA-GALACTOSIDASE GENE
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1997/016555 International Application No.: PCT/CA1996/000723
Publication Date: 09.05.1997 International Filing Date: 01.11.1996
Chapter 2 Demand Filed: 29.05.1997
IPC:
C12N 9/38 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9
Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes
14
Hydrolases (3.)
24
acting on glycosyl compounds (3.2)
38
acting on beta-galactose-glycoside bonds, e.g. beta-galactosidase
Applicants:
NEXIA BIOTECHNOLOGIES, INC. [CA/CA]; 21,111 Lakeshore Road Ste. Anne de Bellevue, Quebec W9X 3Y9, CA
Inventors:
HUANG, Yue; CA
KARATZAS, Costas, N.; CA
LAZARIS-KARATZAS, Anthoula; CA
DELAQUIS, Annick; CA
Agent:
MORROW, Joy, D. ; Smart and Biggar 900-55 Melcalfe Street P.O. Box 2999, Station D Ottawa, Ontario K1P 5Y6, CA
Priority Data:
08/551,45901.11.1995US
Title (EN) ASPERGILLUS NIGER BETA-GALACTOSIDASE GENE
(FR) GENE DE BETA-GALACTOSIDASE D'ASPERGILLUS NIGER
Abstract:
(EN) Disclosed are a cloned cDNA and a cloned genomic DNA, both encoding a $g(b)-galactosidase polypeptide from $i(Aspergillus niger). Also disclosed are $g(b)-galactosidase expression vectors, transformed host cells that overexpress recombinant $i(A. niger) $g(b)-galactosidase, and $i(A. niger) host cell strains with disrupted endogenous $g(b)-galactosidase genes. Also disclosed are transgenic non-human mammals that express $i(A. niger) $g(b)-galactosidase.
(FR) L'invention concerne un ADNc cloné et un ADN génomique cloné codant tous les deux un polypeptide de $g(b)-galactosidase provenant d'$i(Aspergillus niger). Elle concerne également des vecteurs d'expression de $g(b)-galactosidase, des cellules hôtes transformées surexprimant la $g(b)-galactosidase d'$i(Aspergillus niger) et des souches de cellules hôtes d'$i(Aspergillus niger), dont les gènes endogènes de $g(b)-galactosidase présentent des ruptures. Elle concerne enfin des mammifères transgéniques autres que l'homme exprimant la $g(b)-galactosidase d'$i(Aspergillus niger).
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, HU, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, TJ, TM, TR, TT, UA, UG, UZ, VN
African Regional Intellectual Property Organization (ARIPO) (KE, LS, MW, SD, SZ, UG)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
AU1996072740