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1. (WO1997016527) CULTUREWARE FOR BIOARTIFICIAL LIVER
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1997/016527 International Application No.: PCT/US1996/017559
Publication Date: 09.05.1997 International Filing Date: 30.10.1996
IPC:
A61F 2/02 (2006.01) ,A61M 1/16 (2006.01) ,A61M 1/34 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
F
FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
2
Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
02
Prostheses implantable into the body
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
M
DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
1
Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
14
Dialysis systems; Artificial kidneys; Blood oxygenators
16
with membranes
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
M
DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
1
Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
34
Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration, diafiltration
Applicants:
CELLEX BIOSCIENCES, INC. [US/US]; 8500 Evergreen Boulevard Coon Rapids, MN 55433, US (AllExceptUS)
PAGE, Darrell [US/US]; US (UsOnly)
WOJCIECHOWSKI, Robert [US/US]; US (UsOnly)
Inventors:
PAGE, Darrell; US
WOJCIECHOWSKI, Robert; US
Agent:
GOLDMAN, Philip, M. ; Fredrikson & Byron, P.A. 1100 International Centre 900 Second Avenue South Minneapolis, MN 55402, US
Priority Data:
08/550,16230.10.1995US
Title (EN) CULTUREWARE FOR BIOARTIFICIAL LIVER
(FR) MATERIEL DE CULTURE POUR FOIE BIO-ARTIFICIEL
Abstract:
(EN) A disposable cultureware (i.e., bioreactor support module (11) and tube set (12)) assembly (10) for use with a bioartificial liver employing a hollow fiber bioreactor (24 and 26) having an extracapillary flow path connected to both a culture (media) circuit (14) and a hemoperfusion (blood) circuit (16). The assembly (10) includes a gas exchange cartridge (20) operably connected to both the culture (14) and hemoperfusion (16) circuits for controllably gassing the media and blood prior to delivery to the bioreactor (24 and 26). The use of a single gas exchange cartridge (20) within both the media (14) and blood (16) circuits provides advantages in terms of both function and performance as compared to alternative approaches.
(FR) Cette invention se rapporte à un ensemble de matériel de culture jetable (10) (c'est-à-dire un module de support de bio-réacteurs (11) et un jeu de tubes (12)) cet ensemble étant conçu pour être utilisé avec un foie bio-artificiel utilisant un bio-réacteur à fibres creuses (24 et 26) comportant un canal d'écoulement extra-capillaire relié à la fois à un circuit (milieu) de culture (14) et à un circuit (sanguin) d'hémoperfusion (16). Cet ensemble (10) comprend une cartouche d'échange gazeux (20) reliée de façon opérationnelle à la fois au circuit de culture (14) et au circuit d'hémoperfusion (16), pour réguler l'acheminement de gaz dans le milieu de culture et dans le sang avant la libération de ceux-ci dans le bio-réacteur (24 et 26). L'utilisation d'une seule cartouche d'échanges gazeux (20) à la fois dans le circuit du milieu de culture (14) et dans le circuit sanguin (16) présente des avantages en termes à la fois de fonctionnalité et de performances par rapport aux autres approches.
Designated States: JP, US
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP0801674JPH10512159