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1. (WO1997016454) METHOD FOR PREPARING CAMPTOTHECIN DERIVATIVES
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1997/016454 International Application No.: PCT/US1996/017574
Publication Date: 09.05.1997 International Filing Date: 01.11.1996
Chapter 2 Demand Filed: 22.05.1997
IPC:
C07D 491/04 (2006.01) ,C07D 491/22 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
491
Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/-C07D459/290
02
in which the condensed system contains two hetero rings
04
Ortho-condensed systems
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
491
Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/-C07D459/290
22
in which the condensed system contains four or more hetero rings
Applicants:
GLAXO WELLCOME INC. [US/US]; Five Moore Drive Research Triangle Park, NC 27709, US (AllExceptUS)
FANG, Francis, G. [US/US]; US (UsOnly)
XIE, Shiping [CN/US]; US (UsOnly)
Inventors:
FANG, Francis, G.; US
XIE, Shiping; US
Agent:
LEVY, David, J. ; Glaxo Wellcome Inc. Five Moore Drive Research Triangle Park, NC 27709, US
Priority Data:
60/006,13802.11.1995US
Title (EN) METHOD FOR PREPARING CAMPTOTHECIN DERIVATIVES
(FR) PROCEDE POUR PREPARER DES DERIVES DE CAMPTOTHECINE
Abstract:
(EN) The present invention relates to a process for preparing camptothecin and camptothecin analogs of Formula (I) from compounds of Formula (II) and to novel intermediates useful in their preparation, wherein R1 to R6 represent various substituents.
(FR) Cette invention se rapporte à un procédé pour préparer de la camptothécine et des analogues de camptothécine de formule (I) à partir de composés de formule (II), ainsi qu'à de nouveaux intermédiaires servant à leur préparation, formules dans lesquelles R1 à R6 représentent divers substituants.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, HU, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, TJ, TM, TR, TT, UA, UG, US, UZ, VN
African Regional Intellectual Property Organization (ARIPO) (KE, LS, MW, SD, SZ, UG)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
CZPV1998-1338IS4730NO19981970IL124287EP0876373US6143891
JP3499246 JPH11515028 CA2236420EA199800354NZ322318AU1996076038