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1. (WO1997016453) PANCRATISTATINS AND PROCESSES FOR THEIR PRODUCTION
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1997/016453 International Application No.: PCT/US1996/017280
Publication Date: 09.05.1997 International Filing Date: 28.10.1996
Chapter 2 Demand Filed: 30.05.1997
IPC:
C07D 203/26 (2006.01) ,C07D 317/54 (2006.01) ,C07D 317/58 (2006.01) ,C07D 317/60 (2006.01) ,C07D 491/04 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
203
Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
26
condensed with carbocyclic rings or ring systems
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
317
Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
08
having the hetero atoms in positions 1 and 3
44
ortho- or peri-condensed with carbocyclic rings or ring systems
46
condensed with one six-membered ring
48
Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
50
with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
54
Radicals substituted by oxygen atoms
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
317
Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
08
having the hetero atoms in positions 1 and 3
44
ortho- or peri-condensed with carbocyclic rings or ring systems
46
condensed with one six-membered ring
48
Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
50
with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
58
Radicals substituted by nitrogen atoms
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
317
Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
08
having the hetero atoms in positions 1 and 3
44
ortho- or peri-condensed with carbocyclic rings or ring systems
46
condensed with one six-membered ring
48
Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
50
with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
60
Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
491
Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/-C07D459/290
02
in which the condensed system contains two hetero rings
04
Ortho-condensed systems
Applicants:
UNIVERSITY OF FLORIDA [US/US]; 186 Grinter Hall Gainesville, FL 32611, US
Inventors:
HUDLICKY, Tomas; US
KONIGSBERGER, Kurt; AT
MCLAMORE, Sherita, D.; US
RAKESH, Maurya; IN
Agent:
KITCHELL, Barbara, S.; Arnold, White & Durkee P.O. Box 4433 Houston, TX 77210, US
GOWSHALL, Jon, V.; Forrester & Boehmert Franz-Joseph-Strasse 38 D-80801 Munchen, DE
Priority Data:
08/548,36701.11.1995US
Title (EN) PANCRATISTATINS AND PROCESSES FOR THEIR PRODUCTION
(FR) PANCRATISTATINES ET LEURS PROCEDES DE PRODUCTION
Abstract:
(EN) Disclosed are novel pancratistatins and methods for their total asymmetric synthesis. In particular embodiments, processes for the total asymmetric synthesis of (+)-pancratistatin, (-)-pancratistatin, (+)-7-deoxypancratistatin, (-)-7-deoxypancratistatin, truncated pancratistatins, and related derivatives are provided.
(FR) Nouvelles pancratistatines et nouveaux procédés permettant de réaliser leur synthèse asymétrique totale. Selon certaines configurations, l'invention porte sur des procédés de synthèse asymétrique totale de (+)-pancratistatine, (-)-pancratistatine, (+)-7-désoxypancratistatine, (-)-7-désoxypancratistatine, pancratistatines tronquées et dérivés connexes.
Designated States: AL, AM, AT, AU, AZ, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, HU, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, TJ, TM, TR, TT, UA, UG, UZ, VN
African Regional Intellectual Property Organization (ARIPO) (KE, LS, MW, SD, SZ, UG)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
AU1996075983