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1. (WO1997016452) PURINE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1997/016452 International Application No.: PCT/EP1996/004573
Publication Date: 09.05.1997 International Filing Date: 22.10.1996
Chapter 2 Demand Filed: 05.03.1997
IPC:
C07D 473/16 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
473
Heterocyclic compounds containing purine ring systems
02
with oxygen, sulfur, or nitrogen atoms directly attached in positions 2 and 6
16
two nitrogen atoms
Applicants:
NOVARTIS AG [CH/CH]; Schwarzwaldallee 215 CH-4058 Basel, CH (AllExceptUS)
ZIMMERMANN, Jürg [CH/CH]; CH (UsOnly)
CAPRARO, Hans-Georg [CH/CH]; CH (UsOnly)
IMBACH, Patricia [CH/CH]; CH (UsOnly)
FURET, Pascal [FR/FR]; FR (UsOnly)
Inventors:
ZIMMERMANN, Jürg; CH
CAPRARO, Hans-Georg; CH
IMBACH, Patricia; CH
FURET, Pascal; FR
Common
Representative:
NOVARTIS AG; Patent and Trademark Dept. Klybeckstrasse 141 CH-4002 Basle, CH
Priority Data:
2213/9610.09.1996CH
3094/9501.11.1995CH
Title (EN) PURINE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION
(FR) DERIVES PURINES ET PROCEDES DE PREPARATION ASSOCIES
Abstract:
(EN) 2-Amino-6-anilino-purine derivatives of formula (1) in which the symbols are as defined in claim 1, are described. These compounds inhibit p34cdc2/cyclin Bcdc13 kinase and can be used for treatment of hyperproliferative diseases, for example tumour diseases.
(FR) On décrit des dérivés 2-amino-6-anilino-purines de la formule 1 dans laquelle les symboles sont tels que définis dans la revendication 1. Ces composés inhibent la p34cdc2/cycline Bcdc13 kinase et on peut les utiliser dans le traitement de maladies à hyperprolifération, par exemple des tumeurs.
Designated States: AL, AU, BA, BB, BG, BR, CA, CN, CU, CZ, EE, GE, HU, IL, IS, JP, KP, KR, LC, LK, LR, LT, LV, MG, MK, MN, MX, NO, NZ, PL, RO, SG, SI, SK, TR, TT, UA, US, UZ, VN
African Regional Intellectual Property Organization (ARIPO) (KE, LS, MW, SD, SZ, UG)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP0874846US7091346JP4004066 JPH11514336CN1202896CA2234609
AU1996072968