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1. (WO1997016405) NEW COMPOUNDS AND THEIR COMPOSITIONS HAVING ANTI-INFLAMMATORY AND ANTI-THROMBOTIC ACTIVITIES
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1997/016405 International Application No.: PCT/EP1996/004696
Publication Date: 09.05.1997 International Filing Date: 29.10.1996
Chapter 2 Demand Filed: 09.05.1997
IPC:
C07C 203/04 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
203
Esters of nitric or nitrous acid
02
Esters of nitric acid
04
having nitrate groups bound to acyclic carbon atoms
Applicants:
NICOX S.A. [FR/FR]; 45, avenue Kléber F-75116 Paris, FR (AllExceptUS)
DEL SOLDATO, Piero [IT/IT]; IT (UsOnly)
SANNICOLO', Francesco [IT/IT]; IT (UsOnly)
Inventors:
DEL SOLDATO, Piero; IT
SANNICOLO', Francesco; IT
Agent:
SAMA, Daniele ; Sama Patents Via G.B. Morgagni, 2 I-20129 Milano, IT
Priority Data:
MI95A00226331.10.1995IT
Title (EN) NEW COMPOUNDS AND THEIR COMPOSITIONS HAVING ANTI-INFLAMMATORY AND ANTI-THROMBOTIC ACTIVITIES
(FR) NOUVEAUX COMPOSES ET LEURS COMPOSITIONS POSSEDANT DES ACTIVITES ANTI-INFLAMMATOIRES ET ANTITHROMBOTIQUES
Abstract:
(EN) Compounds, or their compositions, of general formula: A - X1 - NO2 or their salts, used as medicaments, wherein: A = R(COX)t; t = 0 or 1; X = O; X0 = X; R being (a) wherein: R1, R2 and R3 are alkyls; X1 is a bivalent linking group chosen among -YO wherein Y is chosen among a linear or when permissible branched C1-C20 alkylene, a cycloalkylene having 5 to 7 carbon atoms optionally substituted; (b) wherein n is an integer from 1 to 6, R2a being H, CH3; r = 0 or 1.
(FR) Ces composés ou leurs compositions, de la formule générale A - X1 - NO2, ou des sels de ceux-ci, sont utilisés en tant que médicaments. Dans cette formule A = R(COX)t, t = 0 ou 1, X = O, XO = X, R répondant à la formule (a) dans laquelle R1, R2 et R3 représentent des alkyles, X1 représente un groupe de liaison bivalent choisi entre -YO, où Y est choisi dans le groupe constitué par alkylène C1-C20 linéaire, ou le cas échéant ramifié, et cycloalkylène possédant 5 à 7 atomes de carbone éventuellement substitués, ou (b) où n est un nombre entier compris entre 1 et 6, R2a représente H, CH3, et r vaut 0 ou 1.
Designated States: AL, AU, BB, BG, BR, CA, CN, CZ, EE, GE, HU, IL, IS, JP, KP, KR, LK, LR, LT, LV, MG, MK, MN, MX, NO, NZ, PL, RO, SG, SI, SK, TR, UA, US, UZ, VN
African Regional Intellectual Property Organization (ARIPO) (KE, LS, MW, SD, SZ, UG)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP0871606RU02165921US6040341JP3880067 JPH11514636 CA2235996
KR1019990067247AU1996074950