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1. (WO1997016204) CONTINUOUS LOW-DOSE CYTOKINE INFUSION THERAPY
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1997/016204 International Application No.: PCT/US1996/017085
Publication Date: 09.05.1997 International Filing Date: 31.10.1996
Chapter 2 Demand Filed: 20.05.1997
IPC:
A61K 38/18 (2006.01) ,A61K 38/19 (2006.01) ,A61K 38/21 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
18
Growth factors; Growth regulators
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
19
Cytokines; Lymphokines; Interferons
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
19
Cytokines; Lymphokines; Interferons
21
Interferons
Applicants:
SCHERING CORPORATION [US/US]; 2000 Galloping Hill Road Kenilworth, NJ 07033-0530, US
Inventors:
CUTLER, David, L.; US
AFFRIME, Melton, B.; US
Agent:
FOULKE, Cynthia, L. ; Schering-Plough Corporation Patent Dept. K-6-1 1990 2000 Galloping Hill Road Kenilworth, NJ 07033-0530, US
Priority Data:
60/006,13002.11.1995US
Title (EN) CONTINUOUS LOW-DOSE CYTOKINE INFUSION THERAPY
(FR) THERAPIE PAR PERFUSION CONTINUE A FAIBLE DOSAGE DE CYTOKINE
Abstract:
(EN) A method is provided for treating conditions that are susceptible of treatment with a cytokine wherein the undesirable side effects normally associated with cytokine administration are diminished or eliminated. The method comprises continuously administering a low dose of a cytokine to an individual afflicted with a condition susceptible of treatment with the cytokine. In a preferred embodiment of the invention, chronic hepatitis C is treated by administering a low dose amount of interferon.
(FR) Cette invention concerne un procédé de traitement de troubles susceptibles d'être traités avec une cytokine, ledit procédé permettant de réduire ou de supprimer les effets secondaires indésirables normalement associés à l'administration de cytokine. Ce procédé consiste à administrer de manière continue une faible dose d'une cytokine à un sujet atteint d'un trouble susceptible d'être traité par ladite cytokine. Selon une réalisation préférée de l'invention, on traite l'hépatite C chronique en administrant une faible dose d'interféron.
Designated States: AL, AM, AU, AZ, BA, BB, BG, BR, BY, CA, CN, CZ, EE, GE, HU, IL, IS, JP, KG, KR, KZ, LC, LK, LR, LT, LV, MD, MG, MK, MN, MX, NO, NZ, PL, RO, RU, SG, SI, SK, TJ, TM, TR, TT, UA, UZ, VN
African Regional Intellectual Property Organization (ARIPO) (KE, LS, MW, SD, SZ, UG)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP0858343JP2000507917 CA2236591CA2329474AU1996074730DK0858343