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1. (WO1997016171) MEMBRANE-FUSIBLE LIPOSOME WITH THE USE OF RECOMBINANT SENDAI VIRUS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1997/016171 International Application No.: PCT/JP1996/003070
Publication Date: 09.05.1997 International Filing Date: 22.10.1996
Chapter 2 Demand Filed: 14.04.1997
IPC:
A61K 9/127 (2006.01) ,C12N 15/88 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
10
Dispersions; Emulsions
127
Liposomes
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
87
Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
88
using micro-encapsulation, e.g. using liposome vesicle
Applicants:
DNAVEC RESEARCH INC. [JP/JP]; 25-11, Kannondai 1-chome Tsukuba-shi Ibaraki 305, JP (AllExceptUS)
NAGAI, Yoshiyuki [JP/JP]; JP (UsOnly)
KATO, Atsushi [JP/JP]; JP (UsOnly)
MURAI, Fukashi [JP/JP]; JP (UsOnly)
SUZUKI, Yosuke [JP/JP]; JP (UsOnly)
TAKEDA, Katsuo [JP/JP]; JP (UsOnly)
HASEGAWA, Mamoru [JP/JP]; JP (UsOnly)
Inventors:
NAGAI, Yoshiyuki; JP
KATO, Atsushi; JP
MURAI, Fukashi; JP
SUZUKI, Yosuke; JP
TAKEDA, Katsuo; JP
HASEGAWA, Mamoru; JP
Agent:
SHIMIZU, Hatsushi; Kantetsu Tsukuba Building 6F 1-1-1, Oroshi-machi Tsuchiura-shi Ibaraki 300, JP
Priority Data:
7/30825201.11.1995JP
Title (EN) MEMBRANE-FUSIBLE LIPOSOME WITH THE USE OF RECOMBINANT SENDAI VIRUS
(FR) LIPOSOME A MEMBRANE FUSIBLE FAISANT APPEL A UN VIRUS SENDAI RECOMBINANT
Abstract:
(EN) A system whereby virions can be efficiently reconstituted from Sendai virus cDNA, thus enabling gene manipulations in Sendai virus. The system makes it possible to produce a recombinant Sendai virus suffering from the deletion or inactivation of one or more functional protein genes and thus having cellular infectivity but no transmissibility. Thus a highly safe DDS with the use of the membrane fusibility of Sendai virus can be provided.
(FR) Cette invention concerne un système permettant de reconstituer efficacement des virions à partir d'ADNc de virus sendai, et d'effectuer ainsi des manipulations géniques dans un virus sendai. Ce système permet de produire un virus sendai présentant une délétion ou une désactivation d'un ou de plusieurs gènes de protéine fonctionnels, et possédant ainsi une infectiosité mais aucune transmissibilité cellulaires. Ce système permet ainsi d'obtenir un DDS d'une grande sécurité en utilisant les capacités de fusion de la membrane d'un virus sendai.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, HU, IL, IS, JP, KE, KG, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, TJ, TM, TR, TT, UA, UG, US, UZ, VN
African Regional Intellectual Property Organization (ARIPO) (KE, LS, MW, SD, SZ, UG)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)
Also published as:
JP3992200AU1996073353