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1. (WO1997015664) INTENSIVE HOMOLOGOUS PROMOTER OBTAINED FROM HAMSTERS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1997/015664 International Application No.: PCT/EP1996/004631
Publication Date: 01.05.1997 International Filing Date: 24.10.1996
Chapter 2 Demand Filed: 26.05.1997
IPC:
C07K 14/47 (2006.01) ,C12N 15/85 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
46
from vertebrates
47
from mammals
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
63
Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
79
Vectors or expression systems specially adapted for eukaryotic hosts
85
for animal cells
Applicants:
DR. KARL THOMAE GMBH [DE/DE]; D-88397 Biberach, DE (AllExceptUS)
ENENKEL, Barbara [DE/DE]; DE (UsOnly)
GANNON, Frank [IE/DE]; DE (UsOnly)
BERGEMANN, Klaus [DE/DE]; DE (UsOnly)
NOE, Wolfgang [DE/DE]; DE (UsOnly)
Inventors:
ENENKEL, Barbara; DE
GANNON, Frank; DE
BERGEMANN, Klaus; DE
NOE, Wolfgang; DE
Agent:
LAUDIEN, Dieter ; Boehringer Ingelheim GmbH A Patente D-55216 Ingelheim am Rhein, DE
Priority Data:
195 39 493.324.10.1995DE
Title (DE) STARKER HOMOLOGER PROMOTOR AUS HAMSTER
(EN) INTENSIVE HOMOLOGOUS PROMOTER OBTAINED FROM HAMSTERS
(FR) PROMOTEUR HOMOLOGUE PUISSANT OBTENU A PARTIR DE HAMSTERS
Abstract:
(DE) Die Erfindung betrifft einen starken homologen Promotor aus Hamster. Insbesondere handelt es sich dabei um den Promotor des Gens, das für das Ubiquitin-S27a-Fusionsprotein kodiert. Der Promotor kann für Verfahren zur Herstellung heterologer Genprodukte in Kulturzellen verwendet werden, insbesondere in CHO-Zellen.
(EN) The invention concerns an intensive homologous promoter obtained from hamsters, in particular the promoter of the gene which codes for ubiquitin-S27a fusion protein. The promoter can be used in processes for preparing heterologous gene products in culture cells, in particular in Chinese hamster ovary cells.
(FR) L'invention concerne un promoteur homologue puissant obtenu à partir de hamsters, et plus particulièrement le promoteur du gène codant la protéine hybride ubiquitine-S27a. Le promoteur peut s'utiliser dans des processus de préparation de produits géniques hétérologues dans des cellules de culture, notamment dans des cellules d'ovaire de hamster chinois.
Designated States: CA, JP, MX, US
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
Publication Language: German (DE)
Filing Language: German (DE)
Also published as:
MXPA/a/1998/002764ES2281905EP0857211EP1803815US6063598JPH11513572
CA2234071PT857211DK0857211