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1. (WO1997015225) AGENT FOR TREATING NEURO-DEGENERATIVE DISORDERS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1997/015225 International Application No.: PCT/RU1996/000306
Publication Date: 01.05.1997 International Filing Date: 23.10.1996
Chapter 2 Demand Filed: 23.05.1997
IPC:
A61K 31/437 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
4353
ortho- or peri-condensed with heterocyclic ring systems
437
the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
Applicants:
ZEFIROV, Nikolai Serafimovich [RU/RU]; RU
AFANASIEV, Andrei Zakharovich [RU/RU]; RU
AFANASIEVA, Svetlana Vasilievna [RU/RU]; RU
BACHURIN, Sergei Olegovich [RU/RU]; RU
TKACHENKO, Sergei Evgenievich [RU/RU]; RU
GRIGORIEV, Vladimir Viktorovich [RU/RU]; RU
JUROVSKAYA, Marina Abramovna [RU/RU]; RU
CHETVERIKOV, Valery Pavlovich [RU/RU]; RU
BUKATINA, Elizaveta Evgenievna [RU/RU]; RU
GRIGORIEVA, Irina Vladimirovna [RU/RU]; RU
Inventors:
ZEFIROV, Nikolai Serafimovich; RU
AFANASIEV, Andrei Zakharovich; RU
AFANASIEVA, Svetlana Vasilievna; RU
BACHURIN, Sergei Olegovich; RU
TKACHENKO, Sergei Evgenievich; RU
GRIGORIEV, Vladimir Viktorovich; RU
JUROVSKAYA, Marina Abramovna; RU
CHETVERIKOV, Valery Pavlovich; RU
BUKATINA, Elizaveta Evgenievna; RU
GRIGORIEVA, Irina Vladimirovna; RU
Agent:
ARGASOV, Oleg Vyacheslavovich; ul. Bolshaya Semenovskaya, 49-404 Moscow, 105023, RU
Priority Data:
9511825223.10.1995RU
Title (EN) AGENT FOR TREATING NEURO-DEGENERATIVE DISORDERS
(FR) AGENT THERAPEUTIQUE CONTRE LES TROUBLES NEURODEGENERATIFS
Abstract:
(EN) Hydrogenated pyrido(4,3-b)indoles of general formula (I) in which R1, R2 and R3 have the meanings indicated in the description and have the properties of NMDA-antagonists and are suitable for use in treating neuro-degenerative disorders, especially Alzheimer's disease.
(FR) Cette invention concerne des pyrido[4,3-b]indoles hydrogénés correspondant à la formule générale (I) où R1, R2 et R3 possèdent des valeurs tel que défini dans la description. Ces pyrido[4,3-b]indoles hydrogénés sont des antagonistes de NMDA et peuvent être utilisés dans le traitement thérapeutique de troubles neurodégénératifs, notamment de la maladie d'Alzheimer.
Designated States: AM, AT, AU, BB, BG, BR, BY, CA, CH, CN, CZ, DE, DK, EE, ES, FI, GB, GE, HU, IS, JP, KE, KG, KP, KR, KZ, LK, LR, LT, LU, LV, MD, MG, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, TJ, TM, TT, UA, UG, US, UZ, VN
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
Publication Language: Russian (RU)
Filing Language: Russian (RU)
Also published as:
ES2188793EP0876818US20010020028US6187785US20020115682US20040044022
US20050096342US20060140866CA2269698DE000069625518AU1996073474PT876818