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1. (WO1997014709) ANTISENSE OLIGOMERS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1997/014709    International Application No.:    PCT/EP1996/004347
Publication Date: 24.04.1997 International Filing Date: 07.10.1996
Chapter 2 Demand Filed:    19.04.1997    
IPC:
C07H 21/00 (2006.01), C12N 15/11 (2006.01)
Applicants: F. HOFFMANN-LA ROCHE AG [CH/CH]; Grenzacherstrasse 124, CH-4070 Basel (CH)
Inventors: GOODNOW, Robert, Alan; (US).
TAM, Steve, Yik-Kai; (US)
Agent: MEZGER, Wolfgang; Grenzacherstrasse 124, CH-4070 Basel (CH)
Priority Data:
60/005,689 13.10.1995 US
Title (EN) ANTISENSE OLIGOMERS
(FR) OLIGOMERES ANTISENS
Abstract: front page image
(EN)Antisense oligomers of formula (I) wherein R¿1?, R¿2? and R¿4? are independently hydrogen, lower alkyl or acyl; R¿3? is hydrogen or lower alkyl; B is a nucleobase or a protected nucleobase; n is 5 to 30; X is NR¿3?R¿4?; Y is OR¿3?, or NHR¿3?; as well as, pharmaceutically acceptable salts thereof.
(FR)On décrit des oligomères antisens de la formule (I), ainsi que des sels de ceux-ci, acceptables sur le plan pharmacologique. Dans cette formule, R¿1?, R¿2? et R¿4? représentent indépendamment hydrogène, alkyle inférieur ou acyle; R¿3? représente hydrogène ou alkyle inférieur; B représente une nucléobase ou une nucléobase protégée; n vaut 5 à 30; X représente NR¿3?R¿4? et Y représente OR¿3? ou NHR¿3?.
Designated States: AL, AU, BA, BB, BG, BR, CA, CN, CZ, EE, GE, HU, IL, IS, JP, KP, KR, LK, LR, LT, LV, MG, MK, MN, MX, NO, NZ, PL, RO, SG, SI, SK, TR, TT, UA, UZ, VN.
African Regional Intellectual Property Organization (KE, LS, MW, SD, SZ, UG)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)