WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO1997013511) METHODS OF INHIBITING PLASMINOGEN ACTIVATOR INHIBITOR 1
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1997/013511    International Application No.:    PCT/US1996/016059
Publication Date: 17.04.1997 International Filing Date: 07.10.1996
Chapter 2 Demand Filed:    09.05.1997    
IPC:
A61K 31/381 (2006.01), A61K 31/4025 (2006.01), A61K 31/4535 (2006.01)
Applicants: ELI LILLY AND COMPANY [US/US]; Lilly Corporate Center, Indianapolis, IN 46285 (US) (For All Designated States Except US).
BERG, David, T. [US/US]; (US) (For US Only).
GRINNELL, Brian, W. [US/US]; (US) (For US Only).
RICHARDSON, Mark, A. [US/US]; (US) (For US Only)
Inventors: BERG, David, T.; (US).
GRINNELL, Brian, W.; (US).
RICHARDSON, Mark, A.; (US)
Agent: SALES, James, J.; Eli Lilly and Company, Lilly Corporate Center, Indianapolis, IN 46285 (US)
Priority Data:
60/005,015 10.10.1995 US
Title (EN) METHODS OF INHIBITING PLASMINOGEN ACTIVATOR INHIBITOR 1
(FR) PROCEDE D'INHIBITON DE L'INHIBITEUR 1 D'ACTIVITEUR DE PLASMINOGENE
Abstract: front page image
(EN)A method of inhibiting plasminogen activator inhibitor 1 comprising administering to a human in need thereof an effective amount of a compound having formula (I), wherein R?1¿ and R?3¿ are independently hydrogen, -CH¿3?, (a) or (b), wherein Ar is optionally s ubstituted phenyl; R?2¿ is selected from the group consisting of pyrrolidine, hexamethyleneimino, and piperidino; or a pharmaceutically acceptable salt or solvate thereof.
(FR)L'invention porte sur un procédé de l'inhibiteur 1 d'activateur de plasminogène, consistant à administrer à une personne qui en a besoin une dose efficace d'un composé représenté par la formule générale (I) dans laquelle R?1¿ et R?3¿ représentent indépendamment hydrogène, -CH¿3?, (a) ou (b), et Ar pouvant éventuellement être par phényle substitué; R?2¿ est sélectionné dans un groupe com posé de pyrrolidine, hexaméthylènimino et pipéridino; ou sur un sel ou solvate de ce composé, admis en pharmacie.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, HU, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, TJ, TM, TR, TT, UA, UG, US, UZ, VN.
African Regional Intellectual Property Organization (KE, LS, MW, SD, SZ, UG)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)