Processing

Please wait...

Settings

Settings

Goto Application

1. WO1997012045 - METHOD OF MAKING A PROTEASE DEFICIENT HOST

Publication Number WO/1997/012045
Publication Date 03.04.1997
International Application No. PCT/US1996/014947
International Filing Date 17.09.1996
Chapter 2 Demand Filed 15.03.1997
IPC
C12N 9/50 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes
14Hydrolases (3.)
48acting on peptide bonds, e.g. thromboplastin, leucine aminopeptidase (3.4)
50Proteinases
C12N 15/67 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
67General methods for enhancing the expression
CPC
C12N 15/67
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
67General methods for enhancing the expression
C12N 9/50
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9Enzymes; Proenzymes; Compositions thereof
14Hydrolases (3)
48acting on peptide bonds (3.4)
50Proteinases ; , e.g. Endopeptidases (3.4.21-3.4.25)
Applicants
  • CHIRON CORPORATION [US]/[US] (AllExceptUS)
  • BISHOP, Robert, J. [US]/[US] (UsOnly)
  • INNIS, Michael, A. [US]/[US] (UsOnly)
Inventors
  • BISHOP, Robert, J.
  • INNIS, Michael, A.
Agents
  • GREEN, Grant, D.
  • GUTH, Joseph, H.
Priority Data
60/004,36127.09.1995US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHOD OF MAKING A PROTEASE DEFICIENT HOST
(FR) PROCEDE D'OBTENTION D'UN HOTE DEFICIENT EN PROTEASES
Abstract
(EN)
This invention relates to improved methods of recombinant protein production in a variety of host cells including yeast and bacteria. The host cells herein are deficient in protease activity, but the deficiency is not a result of a defective protease structural gene.
(FR)
Des procédés améliorés concernant la production de protéines recombinées dans diverses cellules hôtes, y compris les levures et les bactéries. Ces cellules hôtes sont déficientes en activité protéase, mais cette déficience ne résulte pas d'un gène structural de protéase défectueux.
Also published as
Latest bibliographic data on file with the International Bureau