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Machine translation
1. (WO1997012036) BONE STIMULATING FACTOR
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1997/012036    International Application No.:    PCT/CA1996/000653
Publication Date: 03.04.1997 International Filing Date: 26.09.1996
Chapter 2 Demand Filed:    16.04.1997    
IPC:
A61K 38/00 (2006.01), C07K 14/51 (2006.01), C07K 14/52 (2006.01)
Applicants: GENSCI REGENERATION SCIENCES INC. [CA/CA]; 201 - 5090 Explorer Drive, Mississauga, Ontario L4W 4T9 (CA) (For All Designated States Except US).
TAM, Cherk, Shing [CA/CA]; (CA) (For US Only)
Inventors: TAM, Cherk, Shing; (CA)
Agent: HUNT, John, C.; Blake, Cassels & Graydon, Commerce Court West, Box 25, Toronto, Ontario M5L 1A9 (CA).
VOSSIUS & PARTNER; P. O. Box 86 07 67, D-81634 München (DE)
Priority Data:
60/004,314 26.09.1995 US
Title (EN) BONE STIMULATING FACTOR
(FR) FACTEUR DE STIMULATION DE LA CROISSANCE OSSEUSE
Abstract: front page image
(EN)Polypeptides which increase or promote mammalian bone growth, related nucleotide sequences, antibodies, diagnostic kits and treatments. Subsequences of the polypeptide Asp Ser Asp Leu Tyr Ala Glu Leu Arg Cys Met Cys Ile Lys Thr Thr Ser Gly Ile His Pro Lys Asn Ile Gln Ser Leu Glu Val Ile Gly Lys Gly Thr His Cys Asn Gln Val Glu Val Ile Ala Thr Leu Lys Asp Gly Arg Lys Ile Cys Leu Asp Pro Asp Ala Pro Arg Ile Lys Lys Ile Val Gln Lys Lys Leu Ala Gly Asp Glu Ser Ala Asp have been shown to promote growth. Subsequences include Asp Ser Asp Leu Tyr Ala Glu Leu Arg Cys Met Cys Ile Lys Thr Thr Ser Gly Ile His Pro Lys Asn Ile Gln Ser; Ile Lys Thr Thr Ser Gly Ile His Pro Lys Asn Ile Glu Ser; and Cys Met Cys Ile Lys Thr Thr Ser Gly Ile His Pro Lys Asn Ile Gln.
(FR)L'invention concerne des polypeptides qui augmentent ou stimulent la croissance osseuse chez les mammifères, ainsi que des séquences nucléotidiques, des anticorps, des matériels de diagnostic et des traitements. On a mis en évidence que les sous-séquences de polypeptide ci-après stimulent la croissance: Asp Ser Asp Leu Tyr Ala Glu Leu Arg Cys Met Cys Ile Lys Thr Thr Ser Gly Ile His Pro Lys Asn Ile Gln Ser Leu Glu Val Ile Gly Lys Gly Thr His Cys Asn Gln Val Glu Val Ile Ala Thr Leu Lys Asp Gly Arg Lys Ile Cys Leu Asp Pro Asp Ala Pro Arg Ile Lys Lys Ile Val Gln Lys Lys Leu Ala Gly Asp Glu Ser Ala Asp; parmi les sous-séquences figurent: Asp Ser Asp Leu Tyr Ala Glu Leu Arg Cys Met Cys Ile Lys Thr Thr Ser Gly Ile His Pro Lys Asn Ile Gln Ser; Ile Lys Thr Thr Ser Gly Ile His Pro Lys Asn Ile Glu Ser; et Cys Met Cys Ile Lys Thr Thr Ser Gly Ile His Pro Lys Asn Ile Gln.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, HU, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, TJ, TM, TR, TT, UA, UG, US, UZ, VN.
African Regional Intellectual Property Organization (KE, LS, MW, SD, SZ, UG)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)