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Machine translation
1. (WO1997011708) METHOD FOR TREATING ALCOHOLIC LIVER DISEASE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1997/011708    International Application No.:    PCT/US1996/015861
Publication Date: 03.04.1997 International Filing Date: 27.09.1996
Chapter 2 Demand Filed:    10.04.1997    
IPC:
A61K 31/70 (2006.01)
Applicants: EISAI RESEARCH INSTITUTE [US/US]; 4 Corporate Drive, Andover, MA 08180 (US)
Inventors: ROSSIGNOL, Daniel, P.; (US).
THURMAN, Ronald, G.; (US).
CHRIST, William, J.; (US).
LEWIS, Michael, D.; (US)
Agent: SCHAFFER, Robert; Darby & Darby P.C., 805 Third Avenue, New York, NY 10022 (US).
WILDMAN, David, E.; Darby & Darby P.C., 805 Third Avenue, New York, NY 10022 (US)
Priority Data:
60/004,577 29.09.1995 US
60/004,795 02.10.1995 US
Title (EN) METHOD FOR TREATING ALCOHOLIC LIVER DISEASE
(FR) TRAITEMENT DES MALADIES DU FOIE PROVOQUEES PAR L'ALCOOL
Abstract: front page image
(EN)A method for the inhibition and amelioration of alcoholic liver disease in a mammal in need of such treatment by administering novel analogs of Lipid A which act as endotoxin antagonists. These antagonists compounds are found to inhibit the swift increase in alcohol metabolism which typically accompanies ingestion of alcohol and which may lead to the pathophysiological abnormalities associated with alcoholic liver disease.
(FR)L'invention concerne un traitement permettant de guérir partiellement ou totalement les maladies du foie provoquées par l'alcool. Ce traitement consiste à administrer à un mammifère malade de nouveaux analogues du lipide A qui agissent en tant qu'antagonistes des endotoxines. Il a été découvert que ces antagonistes inhibent l'augmentation rapide du métabolisme de l'alcool qui accompagne généralement l'absorption d'alcool et qui peut conduire aux troubles pathophysiologiques caractéristiques des maladies du foie dues à l'alcool.
Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GE, HU, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, TJ, TM, TR, TT, UA, UG, UZ, VN.
African Regional Intellectual Property Organization (KE, LS, MW, SD, SZ, UG)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)