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Machine translation
1. (WO1997010845) AN IMMUNOSTIMULANT AND ANTINEOPLASTIC GLYCAN OBTAINED FROM MYCOBACTERIUM VACCAE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1997/010845    International Application No.:    PCT/US1996/015011
Publication Date: 27.03.1997 International Filing Date: 18.09.1996
Chapter 2 Demand Filed:    11.03.1997    
IPC:
A61K 39/04 (2006.01), A61K 39/39 (2006.01)
Applicants: BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS [US/US]; 352 Henry Administration Building, 506 South Wright Street, Urbana, IL 61801 (US) (For All Designated States Except US).
GROVES, Michael, J. [US/US]; (US) (For US Only).
KLEGERMAN, Melvin, E. [US/US]; (US) (For US Only)
Inventors: GROVES, Michael, J.; (US).
KLEGERMAN, Melvin, E.; (US)
Agent: CLOUGH, David, W.; Marshall, O'Toole, Gerstein, Murray & Borun, 6300 Sears Tower, 233 South Wacker Drive, Chicago, IL 60606 (US)
Priority Data:
60/003,892 18.09.1995 US
Title (EN) AN IMMUNOSTIMULANT AND ANTINEOPLASTIC GLYCAN OBTAINED FROM MYCOBACTERIUM VACCAE
(FR) UN GLYCANNE IMMUNOSTIMULANT ET ANTINEOPLASIQUE OBTENU A PARTIR DE MYCOBACTERIUM VACCAE
Abstract: front page image
(EN)The present invention is a glycan compound with antineoplastic and immunostimulant properties for treating human cancers and as an adjuvant in the formulation of a tuberculosis vaccine, said compound containing at least one component from the class of sugars including arabinose, mannose, glucose and galactose, together with a peptide side chain, having an approximate 60-65 kDa molecular weight, and being readily water-soluble and heat-stable. The invention also is comprised of a process for extracting the glycan compound from the $i(Mycobacterium vaccae), a non-pathogenic, rapid growing member of the mycobacteria.
(FR)La présente invention concerne un glycanne ayant des propriétés antinéoplasiques et immunostimulantes, pour traiter les cancers humains et comme adjuvant pour la formulation d'un vaccin anti-tuberculeux. Ce composé contient au moins un composant de la classe des sucres, dont l'arabinose, le mannose, le glucose et le galactose, ainsi qu'une chaîne latérale peptidique, ayant une poids moléculaire correspondant à environ 60-65 kDa. Ce composé se dissout facilement dans l'eau et est stable à la chaleur. L'invention concerne également un procédé pour extraire le glycanne de $i(Mycobacterium vaccae), une mycobactérie non pathogène à croissance rapide.
Designated States: CA, JP, US.
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE).
Publication Language: English (EN)
Filing Language: English (EN)