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Machine translation
1. (WO1997009877) CURCUMIN (DIFERULOYLMETHANE) INHIBITION OF NF$g(k)B ACTIVATION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1997/009877    International Application No.:    PCT/US1996/014725
Publication Date: 20.03.1997 International Filing Date: 13.09.1996
Chapter 2 Demand Filed:    11.04.1997    
IPC:
A61K 31/12 (2006.01)
Applicants: RESEARCH DEVELOPMENT FOUNDATION [US/US]; 402 North Division Street, Carson City, NV 89703 (US)
Inventors: AGGARWAL, Bharat, B.; (US)
Agent: WEILER, James, F.; Suite 1560, 1 Riverway, Houston, TX 77056 (US)
Priority Data:
60/003,799 14.09.1995 US
Title (EN) CURCUMIN (DIFERULOYLMETHANE) INHIBITION OF NF$g(k)B ACTIVATION
(FR) INHIBITION DE L'ACTIVATION DU FACTEUR NF-$g(k)B PAR LE CURCUMIN (DIFERULOYLMETHANE)
Abstract: front page image
(EN)The present invention provides a method of inhibiting the activation of the NF-$g(k)B transcription factor in an animal in need of such treatment comprising the step of administering to said animal a pharmacologically effective dose of curcumin. Also provided is a method of inhibiting the nuclear translocation of the p65 subunit of the NF-$g(k)B transcription factor in a cell or in an animal in need of such treatment comprising the step of administering to said animal a pharmacologically effective dose of curcumin.
(FR)La présente invention concerne un procédé pour inhiber l'activation du facteur de transcription NF-$g(k)B chez un animal nécessitant un tel traitement, consistant à lui administrer une dose de curcumin suffisante pour avoir un effet pharmacologique. L'invention concerne également un procédé pour inhiber la translocation nucléaire de la sous-unité p65 du facteur de transcription NF-$g(k)B dans une cellule ou chez un animal nécessitant un tel traitement, consistant à administrer une dose de curcumin suffisante pour avoir un effet pharmacologique.
Designated States: AM, AT, AU, BB, BG, BR, BY, CA, CH, CN, CZ, DE, DK, EE, ES, FI, GB, GE, HU, IL, IS, JP, KE, KG, KP, KR, KZ, LK, LR, LT, LU, LV, MD, MG, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, TJ, TM, TT, UA, UG, UZ, VN.
African Regional Intellectual Property Organization (KE, LS, MW, SD, SZ, UG)
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)