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1. (WO1997002266) PYRROLOPYRIMIDINES AND PROCESSES FOR THE PREPARATION THEREOF
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1997/002266 International Application No.: PCT/EP1996/002728
Publication Date: 23.01.1997 International Filing Date: 24.06.1996
Chapter 2 Demand Filed: 07.12.1996
IPC:
C07D 207/34 (2006.01) ,C07D 471/14 (2006.01) ,C07D 487/04 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
207
Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
02
with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
30
having two double bonds between ring members or between ring members and non-ring members
34
with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
471
Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/-C07D463/251
12
in which the condensed system contains three hetero rings
14
Ortho-condensed systems
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
487
Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/-C07D477/183
02
in which the condensed system contains two hetero rings
04
Ortho-condensed systems
Applicants:
NOVARTIS AG [CH/CH]; Schwarzwaldallee 215 CH-4058 Basel, CH (AllExceptUS)
TRAXLER, Peter [CH/CH]; CH (UsOnly)
BOLD, Guido [CH/CH]; CH (UsOnly)
BRILL, Wolfgang, Karl-Diether [DE/DE]; DE (UsOnly)
FREI, Jörg [CH/CH]; CH (UsOnly)
Inventors:
TRAXLER, Peter; CH
BOLD, Guido; CH
BRILL, Wolfgang, Karl-Diether; DE
FREI, Jörg; CH
Common
Representative:
NOVARTIS AG; Patent and Trademark Dept. Klybeckstrasse 141 CH-4002 Basle, CH
Priority Data:
0255/9601.02.1996CH
1224/9613.05.1996CH
1976/9506.07.1995CH
2498/9501.09.1995CH
3198/9510.11.1995CH
Title (EN) PYRROLOPYRIMIDINES AND PROCESSES FOR THE PREPARATION THEREOF
(FR) PYRROLOPYRIMIDINES ET LEURS PROCEDES DE PREPARATION
Abstract:
(EN) Described are 7H-pyrrolo[2,3-d]pyrimidine derivatives of formula (I) wherein the symbols are as defined in claim 1. Those compounds inhibit tyrosine protein kinase and can be used in the treatment of hyperproliferative diseases, for example tumour diseases.
(FR) L'invention a pour objet des dérivés de 7H-pyrrolo(2,3-d)pyrimidine de formule (I) dans laquelle les symboles sont ceux définis dans la revendication 1. Ces composés inhibent la tyrosine protéine kinase et sont utiles pour traiter les maladies hyperprolifératives, par exemple, les maladies tumorales.
Designated States: AL, AU, BB, BG, BR, CA, CN, CZ, EE, GE, HU, IL, IS, JP, KP, KR, LK, LR, LT, LV, MG, MK, MN, MX, NO, NZ, PL, RO, SG, SI, SK, TR, TT, UA, US, UZ, VN
African Regional Intellectual Property Organization (ARIPO) (KE, LS, MW, SD, SZ, UG)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
CZPV1998-15NO19975956SK398TR1998/00012SG50273VN2548
IL122855EP0836605US6140332JP4146514 JPH11508570CN1194647
CA2224435EA199800116KR1019990028756NZ312665AU1996064148DK0836605