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1. WO1996040874 - METHODS FOR OBTAINING COMPOSITIONS ENRICHED FOR HEMATOPOIETIC STEM CELLS AND ANTIBODIES FOR USE THEREIN

Publication Number WO/1996/040874
Publication Date 19.12.1996
International Application No. PCT/EP1996/002462
International Filing Date 06.06.1996
Chapter 2 Demand Filed 21.10.1996
IPC
A61K 35/28 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
C07K 16/28 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
28against receptors, cell surface antigens or cell surface determinants
C12N 5/0789 2010.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
07Animal cells or tissues
071Vertebrate cells or tissues, e.g. human cells or tissues
078Cells from blood or from the immune system
0789Stem cells; Multipotent progenitor cells
C12P 21/08 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
21Preparation of peptides or proteins
08Monoclonal antibodies
CPC
A61K 35/28
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
C07K 16/28
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
28against receptors, cell surface antigens or cell surface determinants
C12N 5/0647
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor;
06Animal cells or tissues; Human cells or tissues
0602Vertebrate cells
0634Cells from the blood or the immune system
0647Haematopoietic stem cells; Uncommitted or multipotent progenitors
Applicants
  • NOVARTIS AG [CH]/[CH] (AL, AM, AT, AU, AZ, BB, BE, BF, BG, BJ, BR, BY, CA, CF, CG, CH, CI, CM, CN, CZ, DE, DK, EE, ES, FI, FR, GA, GB, GE, GN, GR, HU, IE, IL, IS, IT, JP, KE, KG, KP, KR, KZ, LK, LR, LS, LT, LU, LV, MC, MD, MG, MK, ML, MN, MR, MW, MX, NE, NL, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SN, SZ, TD, TG, TJ, TM, TR, TT, UA, UG, UZ, VN)
  • SYSTEMIX, INC. [US]/[US]
  • NOVARTIS-ERFINDUNGEN VERWALTUNGSGESELLSCHAFT M.B.H [AT]/[AT] (AT)
Inventors
  • HILL, Beth, Louise
  • ROZLER, Elen
  • CHEN, Benjamin, P.
Common Representative
  • NOVARTIS AG
Priority Data
08/481,68607.06.1995US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHODS FOR OBTAINING COMPOSITIONS ENRICHED FOR HEMATOPOIETIC STEM CELLS AND ANTIBODIES FOR USE THEREIN
(FR) PROCEDES D'OBTENTION DE COMPOSITIONS ENRICHIES EN CELLULES SOUCHES HEMATOPOIETIQUES ET ANTICORPS UTILISES A CET EFFET
Abstract
(EN)
A method for obtaining human hematopoietic stem cells is provided by enrichment for stem cells using a novel stem cell marker. Compositions obtained thereby and reagents for use therein are also provided.
(FR)
La présente invention décrit un procédé d'obtention de cellules souches hématopoïétiques humaines par le biais d'un enrichissement en cellules souches effectué par un nouveau marqueur des cellules souches. L'invention se rapporte également aux compositions ainsi obtenues et aux réactifs utilisés dans celles-ci.
Also published as
Latest bibliographic data on file with the International Bureau