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1. WO1996040770 - ANTI-FUNGAL D-AMINO ACID HISTATIN-BASED PEPTIDES

Publication Number WO/1996/040770
Publication Date 19.12.1996
International Application No. PCT/US1996/009962
International Filing Date 07.06.1996
Chapter 2 Demand Filed 30.12.1996
IPC
A61K 38/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
C07K 14/47 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
46from vertebrates
47from mammals
CPC
A61K 38/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
A61P 31/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
04Antibacterial agents
A61P 31/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
10Antimycotics
C07K 14/4723
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
46from vertebrates
47from mammals
4701not used
4723Cationic antimicrobial peptides, e.g. defensins
Applicants
  • PERIODONTIX, INC. [US]/[US] (AllExceptUS)
  • TRUSTEES OF BOSTON UNIVERSITY [US]/[US] (AllExceptUS)
  • OPPENHEIM, Frank, G. [US]/[US] (UsOnly)
  • XU, Tao [CN]/[US] (UsOnly)
  • SPACCIAPOLI, Peter [US]/[US] (UsOnly)
  • ROBERTS, F., Donald [US]/[US] (UsOnly)
  • FRIDEN, Phillip, M. [US]/[US] (UsOnly)
Inventors
  • OPPENHEIM, Frank, G.
  • XU, Tao
  • SPACCIAPOLI, Peter
  • ROBERTS, F., Donald
  • FRIDEN, Phillip, M.
Agents
  • BROOK, David, E.
Priority Data
08/485,27307.06.1995US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) ANTI-FUNGAL D-AMINO ACID HISTATIN-BASED PEPTIDES
(FR) PEPTIDES ANTIFONGIQUES A BASE D'HISTATINE A D-AMINOACIDES
Abstract
(EN)
D-amino acid histatins and histatin-based peptides and methods for treatment of fungal or bacterial infection are described. These D-amino acid histatins and histatin-based peptides are longer-acting anti-fungal or anti-bacterial agents than their L-enantiomeric analogues.
(FR)
L'invention porte sur des histatines à D-aminoacides et des peptides à base desdites histatines, ainsi que des procédés utilisés pour le traitement d'infections mycosiques ou bactériennes. Lesdits histatines et peptides sont des agents antifongiques et antibactériens à plus longue durée d'action que leurs analogues L-énantiomères.
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