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1. WO1996040621 - METHODS AND COMPOUNDS FOR DIAGNOSING CORONARY ARTERY DISEASE

Publication Number WO/1996/040621
Publication Date 19.12.1996
International Application No. PCT/US1996/007811
International Filing Date 31.05.1996
Chapter 2 Demand Filed 31.12.1996
IPC
C07C 217/02 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
217Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
02having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
C07C 247/04 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
247Compounds containing azido groups
02with azido groups bound to acyclic carbon atoms of a carbon skeleton
04being saturated
C07C 255/24 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
255Carboxylic acid nitriles
01having cyano groups bound to acyclic carbon atoms
24containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the same saturated acyclic carbon skeleton
C07C 317/28 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
317Sulfones; Sulfoxides
26having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
28with sulfone or sulfoxide groups bound to acyclic carbon atoms of the carbon skeleton
C07C 323/25 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
323Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
23containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
24having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
25the carbon skeleton being acyclic and saturated
CPC
C07C 217/02
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
217Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
02having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
C07C 247/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
247Compounds containing azido groups
02with azido groups bound to acyclic carbon atoms of a carbon skeleton
04being saturated
C07C 255/24
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
255Carboxylic acid nitriles
01having cyano groups bound to acyclic carbon atoms
24containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the same saturated acyclic carbon skeleton
C07C 317/28
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
317Sulfones; Sulfoxides
26having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
28with sulfone or sulfoxide groups bound to acyclic carbon atoms of the carbon skeleton
C07C 323/25
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
323Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
23containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
24having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
25the carbon skeleton being acyclic and saturated
Applicants
  • GENSIA, INC. [US]/[US]
Inventors
  • METZNER, Ernest, K.
  • ERION, Mark, D.
Agents
  • WOLFF, Jessica, R.
  • VIERING, JENTSCHURA & PARTNER
Priority Data
08/482,43507.06.1995US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHODS AND COMPOUNDS FOR DIAGNOSING CORONARY ARTERY DISEASE
(FR) PROCEDES ET COMPOSES DE DIAGNOSTIC DES AFFECTIONS DES ARTERES CORONAIRES
Abstract
(EN)
The present invention relates generally to methods of diagnosis, evaluation and treatment of coronary artery disease in mammals using substituted catecholamines and compounds therefore. It also relates to the preparation, use and administration of these compounds which are useful in the diagnosis, evaluation and treatment of coronary artery disease by means of a feedback controlled drug delivery system that delivers exercise simulating agents which are capable of eliciting acute responses similar to those elicited by aerobic exercise.
(FR)
La présente invention concerne d'une manière générale des procédés de diagnostic, d'évaluation et de traitement des affections des artères coronaires chez les mammifères au moyen de catécholamines substituées et de composés destinés à ces usages. L'invention concerne aussi la préparation, l'emploi et l'administration de ces composés, qui sont utiles dans le diagnostic, l'évaluation et le traitement d'affections des artères coronaires au moyen d'un système d'apport de médicaments commandé par rétroaction, qui fournit des agents de simulation de l'exercice physique capables de déclencher des réactions intenses, similaires à celles que produisent les exercices d'aérobic.
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