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1. WO1996040364 - ELECTROTRANSPORT AGENT DELIVERY METHOD AND APPARATUS

Publication Number WO/1996/040364
Publication Date 19.12.1996
International Application No. PCT/US1996/009989
International Filing Date 07.06.1996
Chapter 2 Demand Filed 27.12.1996
IPC
A61N 1/32 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
1Electrotherapy; Circuits therefor
18Applying electric currents by contact electrodes
32alternating or intermittent currents
CPC
A61N 1/044
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
1Electrotherapy; Circuits therefor
02Details
04Electrodes
0404for external use
0408Use-related aspects
0428Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
0432Anode and cathode
044Shape of the electrode
A61N 1/0448
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
1Electrotherapy; Circuits therefor
02Details
04Electrodes
0404for external use
0408Use-related aspects
0428Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
0448Drug reservoir
A61N 1/325
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
1Electrotherapy; Circuits therefor
18Applying electric currents by contact electrodes
32alternating or intermittent currents
325for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
Applicants
  • ALZA CORPORATION [US]/[US] (AllExceptUS)
  • PHIPPS, J., Bradley [US]/[US] (UsOnly)
  • LATTIN, Gary, A. [US]/[US] (UsOnly)
  • HAAK, Ronald, P. [US]/[US] (UsOnly)
  • THEEUWES, Felix [BE]/[US] (UsOnly)
  • GUPTA, Suneel [IN]/[US] (UsOnly)
Inventors
  • PHIPPS, J., Bradley
  • LATTIN, Gary, A.
  • HAAK, Ronald, P.
  • THEEUWES, Felix
  • GUPTA, Suneel
Agents
  • MILLER, D., Byron
Priority Data
08/483,06907.06.1995US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) ELECTROTRANSPORT AGENT DELIVERY METHOD AND APPARATUS
(FR) PROCEDE ET APPAREIL D'ADMINISTRATION D'AGENTS PAR ELECTROTRANSPORT
Abstract
(EN)
An electrotransport agent delivery device (10) for delivering a therapeutic agent through intact skin, and a method of operating same, is provided. The device applies a pulsing electrotransport current wherein current pulses have a magnitude above a critical level (Ic) at which the skin is transformed into a higher electrotransport delivery efficiency (E) state. Most preferably the length of the applied current pulses is at least 5 msec and preferably at least 10 msec.
(FR)
Dispositif (10) d'administration d'agents par électrotransport permettant d'administrer un agent thérapeutique au travers de la peau sans entamer celle-ci, et procédé d'utilisation de ce dispositif. Le dispositif applique un courant d'électrotransport à impulsions, ces impulsions ayant une amplitude supérieure à un niveau critique (Ic) à partir duquel la peau accède à un état où l'efficacité (E) de l'administration par électrotransport est plus élevée. Idéalement, la durée des impulsions électriques appliquées est d'au moins 5 msec, et de préférence d'au moins 10 msec.
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