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1. WO1996040124 - ANTI-VIRAL COMPOUNDS

Publication Number WO/1996/040124
Publication Date 19.12.1996
International Application No. PCT/US1996/008830
International Filing Date 05.06.1996
Chapter 2 Demand Filed 10.10.1996
IPC
C07D 235/30 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
235Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
02condensed with carbocyclic rings or ring systems
04Benzimidazoles; Hydrogenated benzimidazoles
24with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
30Nitrogen atoms not forming part of a nitro radical
CPC
A61P 11/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
A61P 31/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
C07D 235/30
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
235Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
02condensed with carbocyclic rings or ring systems
04Benzimidazoles; Hydrogenated benzimidazoles
24with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
30Nitrogen atoms not forming part of a nitro radical
Applicants
  • ELI LILLY AND COMPANY [US]/[US]
Inventors
  • MILLER, Shawn, C.
  • VICTOR, Frantz
  • SATTELBERG, Thomas, R., S.
  • SPITZER, Wayne, A.
  • TEBBE, Mark, J.
Agents
  • McCLAIN, Janet, T.
Priority Data
08/482,04107.06.1995US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) ANTI-VIRAL COMPOUNDS
(FR) COMPOSES ANTIVIRAUX
Abstract
(EN)
The present application provides a series of benzimidazole compounds which inhibit the growth of picornaviruses, such as rhinoviruses, enteroviruses, cardioviruses, polioviruses, coxsachieviruses of the A and B groups, echo virus and Mengo virus. Such compounds are also useful as intermediates for preparing additional benzimidazole antiviral compounds.
(FR)
La présente invention se rapporte à une série de composés de benzimidazole inhibant la croissance des picornavirus, tels que les rhinovirus, les entérovirus, les cardiovirus, les poliovirus, les virus Coxsackie des groupes A et B, l'écho virus ainsi que le virus de Mengo. De tels composés servent d'intermédiaires dans la préparation de composés additionnels antiviraux de benzimidazole.
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