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1. WO1996039123 - ORAL VETERINARY FLUOROQUINOLONE ANTIBACTERIAL COMPOSITION FOR EXTENDED DURATION OF THERAPY AND METHOD OF TREATING

Publication Number WO/1996/039123
Publication Date 12.12.1996
International Application No. PCT/US1996/006961
International Filing Date 22.05.1996
Chapter 2 Demand Filed 20.12.1996
IPC
A61K 9/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
A61K 31/496 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
CPC
A61K 31/496
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495having six-membered rings with two ; or more; nitrogen atoms as the only ring heteroatoms, e.g. piperazine ; or tetrazines
496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
A61K 9/0068
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
0012Galenical forms characterised by the site of application
0053Mouth and digestive tract, i.e. intraoral and peroral administration
0068Rumen, e.g. rumen bolus
A61P 31/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
04Antibacterial agents
Y10S 514/937
YSECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
10TECHNICAL SUBJECTS COVERED BY FORMER USPC
STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
514Drug, bio-affecting and body treating compositions
937Dispersion or emulsion
Y10S 514/944
YSECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
10TECHNICAL SUBJECTS COVERED BY FORMER USPC
STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
514Drug, bio-affecting and body treating compositions
944Gel
Applicants
  • AMERICAN CYANAMID COMPANY [US]/[US]
Inventors
  • DANIELSON, Douglas, W.
  • NICHOLS, Eric
  • HUSBAND, Brent
Agents
  • LAVALLEYE, Jean-Paul
Priority Data
08/470,40506.06.1995US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) ORAL VETERINARY FLUOROQUINOLONE ANTIBACTERIAL COMPOSITION FOR EXTENDED DURATION OF THERAPY AND METHOD OF TREATING
(FR) COMPOSITION ANTIBACTERIENNE ORALE DE FLUOROQUINOLONE A USAGE VETERINAIRE, POUR DES TRAITEMENTS DE LONGUE DUREE, ET PROCEDE DE TRAITEMENT ASSOCIE
Abstract
(EN)
The present invention concerns a formulation for an oral veterinary composition containing a fluoroquinolone antimicrobial agent or a pharmaceutically acceptable salt thereof, and a method of treating a microbial infection in a ruminant. The present veterinary composition, when administered orally to a ruminating animal (e.g., a cow or a feedlot calf), allows the fluoroquinolone to be readily and extensively absorbed from the rumen into the circulating blood and provides an unexpectedly extended duration of therapeutic antimicrobial blood level.
(FR)
La présente invention concerne une formulation vétérinaire administrée per os contenant comme agent antibactérien une fluoroquinolone, ou un sel de celle-ci pharmaceutiquement acceptable ainsi qu'un procédé pour traiter des infections microbiennes chez un ruminant. La présente composition vétérinaire, quand elle est administrée per os à un ruminant (vache ou veau élevé en batterie), permet une absorption facile et complète de la fluoroquinolone depuis le rumen dans le sang et elle permet de conserver un niveau thérapeutique de l'agent antibactérien dans le sang pendant une durée inattendue.
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