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1. WO1996038179 - PREPARATION FOR DIAGNOSTIC OF THE METABOLIC SYNDROME AND DISEASES INCLUDING THE SYNDROME

Publication Number WO/1996/038179
Publication Date 05.12.1996
International Application No. PCT/SE1996/000708
International Filing Date 30.05.1996
Chapter 2 Demand Filed 27.12.1996
IPC
G01N 33/74 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
74involving hormones
CPC
A61K 31/573
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives, e.g. steroids
57substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane, progesterone
573substituted in position 21, e.g. cortisone, dexamethasone, prednisone ; or aldosterone
G01N 33/743
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
74involving hormones ; or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
743Steroid hormones
Applicants
  • CORTENDO AB [SE]/[SE] (AllExceptUS)
  • MÅRIN, Per [SE]/[SE] (UsOnly)
Inventors
  • MÅRIN, Per
Agents
  • GÖTEBORGS PATENTBYRÅ
Priority Data
9501991-530.05.1995SE
Publication Language English (EN)
Filing Language Swedish (SV)
Designated States
Title
(EN) PREPARATION FOR DIAGNOSTIC OF THE METABOLIC SYNDROME AND DISEASES INCLUDING THE SYNDROME
(FR) PREPARATION D'UN SYSTEME DE DIAGNOSTIC DU SYNDROME METABOLIQUE ET DE MALADIES PRESENTANT CE SYNDROME
Abstract
(EN)
The use of cortisol agonist for preparing a system for diagnosis of the metabolic syndrome and related conditions as belly fatness, insulin resistancy including increased risk of developing senile diabetes, i.e. diabetes type II, high blood fats and high blood pressure, in which system the dose of cortisol agonist is in an interval where a difference is obtained in the inhibitory effect of the autoproduction of cortisol in individuals suffering from the metabolic syndrome, compared to normal values.
(FR)
On utilise des agonistes du cortisol pour préparer un système de diagnostic du syndrome métabolique et d'états associés, tels que le gonflement du ventre, la résistance à l'insuline, y compris l'accroissement du risque d'évolution de diabètes séniles, c'est-à-dire de diabètes de type II, un taux élevé de cholestérol et une tension élevée, la dose d'agoniste de cortisol se trouvant dans un intervalle dans lequel on obtient une différence dans l'effet inhibiteur de l'auto-production automatique de cortisol chez des individus atteints par le syndrome métabolique, par rapport à des valeurs normales.
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