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1. WO1996031480 - NOVEL HETEROCYCLIC COMPOUNDS

Publication Number WO/1996/031480
Publication Date 10.10.1996
International Application No. PCT/DK1996/000154
International Filing Date 01.04.1996
IPC
C07D 223/20 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
223Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
14condensed with carbocyclic rings or ring systems
18Dibenzazepines; Hydrogenated dibenzazepines
20Dibenz azepines; Hydrogenated dibenz azepines
C07D 281/02 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
281Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
02Seven-membered rings
CPC
C07D 223/20
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
223Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
14condensed with carbocyclic rings or ring systems
18Dibenzazepines; Hydrogenated dibenzazepines
20Dibenz [b, e] azepines; Hydrogenated dibenz [b, e] azepines
C07D 281/02
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
281Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
02Seven-membered rings
Applicants
  • NOVO NORDISK A/S [DK]/[DK] (AllExceptUS)
  • ANDERSEN, Knud, Erik [DK]/[DK] (UsOnly)
  • OLSEN, Uffe, Bang [DK]/[DK] (UsOnly)
  • ANDERSEN, Henrik, Sune [DK]/[DK] (UsOnly)
  • HOHLWEG, Rolf [DE]/[DK] (UsOnly)
  • JØRGENSEN, Tine, Krogh [DK]/[DK] (UsOnly)
  • MADSEN, Peter [DK]/[DK] (UsOnly)
Inventors
  • ANDERSEN, Knud, Erik
  • OLSEN, Uffe, Bang
  • ANDERSEN, Henrik, Sune
  • HOHLWEG, Rolf
  • JØRGENSEN, Tine, Krogh
  • MADSEN, Peter
Common Representative
  • NOVO NORDISK A/S
Priority Data
0420/9507.04.1995DK
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) NOVEL HETEROCYCLIC COMPOUNDS
(FR) NOUVEAUX COMPOSES HETEROCYCLIQUES
Abstract
(EN)
A compound of formula (I) in which Z is selected from (a), (b), (c) and (d). The present invention relates to novel N-substituted amino acids and esters thereof in which a substituted alkyl chain forms part of the N-substituent or salts thereof, to methods for their preparation, to compositions containing them, and to their use for the clinical treatment of painful, hyperalgesic and/or inflammatory conditions in which C-fibers play a pathophysiological role by eliciting neurogenic pain or inflammation.
(FR)
La présente invention décrit un composé de formule (I). Z est choisi parmi (a), (b), (c) et (d). La présente invention se rapporte à de nouveaux aminoacides N-substitués et leurs esters dans lesquels une chaîne alkyle substituée fait partie du substituant N ou de ses sels, à leur procédé de fabrication, aux compositions les contenant et à leur utilisation pour le traitement clinique d'états douloureux, hyperalgésiques et/ou inflammatoires dans lesquelles les fibres C jouent un rôle pathophysiologique en provoquant une douleur ou inflammation neurogène.
Also published as
Latest bibliographic data on file with the International Bureau