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1. (WO1996025179) COMPOSITION AND METHOD FOR PRODUCTION OF TRANSFORMED CELLS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1996/025179 International Application No.: PCT/US1996/002136
Publication Date: 22.08.1996 International Filing Date: 16.02.1996
Chapter 2 Demand Filed: 19.08.1996
IPC:
A61K 48/00 (2006.01) ,A61L 27/36 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
48
Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
L
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27
Materials for prostheses or for coating prostheses
36
containing ingredients of undetermined constitution or reaction products thereof
Applicants:
PURDUE RESEARCH FOUNDATION [US/US]; Room 328 1650 Engineering Administration Building West Lafayette, IN 47907-1650, US
BONADIO, Jeffrey [US/US]; US
Inventors:
BONADIO, Jeffrey; US
BADYLAK, Stephen, F.; US
VOYTIK, Sherry; US
Agent:
LAMMERT, Steven, R. ; Barnes & Thornburg 1313 Merchants Bank Building 11 South Meridian Street Indianapolis, IN 46204, US
Priority Data:
08/390,70017.02.1995US
Title (EN) COMPOSITION AND METHOD FOR PRODUCTION OF TRANSFORMED CELLS
(FR) COMPOSITION ET PROCEDE POUR LA PRODUCTION DE CELLULES TRANSFORMEES
Abstract:
(EN) A composition useful for the production of transformed eukaryotic cells is described. The composition comprises submucosal tissue and a nucleic acid sequence. The nucleic acid sequence is typically recombinant DNA including gene(s) encoding for one or more biofunctional proteins. The submucosal tissue component of the present composition comprises the tunica submucosa of vertebrate intestine delaminated from the tunica muscularis and at least the luminal portion of the tunica mucosa. Injection or implantation of the composition into a host induces the formation of transformed cells capable of expressing gene(s) encoded by the nucleic acid sequence.
(FR) Composition utile pour la production de cellules eucaryotes transformées. Cette composition comprend du tissu sous-muqueuse et une séquence nucléotidique. La séquence nucléotidique est généralement de l'ADN de recombinaison comportant un ou plusieurs gène(s) codant pour une ou plusieurs protéines biofonctionnelles. La composante de tissu sous-muqueuse de la composition selon l'invention comprend la tunique sous-muqueuse d'intestin de vertébré délamifiée de la tunique musculeuse et au moins la partie située au niveau de la lumière de la tunique muqueuse. L'injection ou l'implantation de la composition dans un hôte permet d'induire la formation de cellules transformées capables d'exprimer un ou plusieurs gène(s) codé(s) par la séquence nucléotidique.
Designated States: AU, BR, CA, HU, JP, KR, MX, PL, SG
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
Publication Language: English (EN)
Filing Language: English (EN)