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1. (WO1996009044) COMPOSITIONS USEFUL FOR THE PREPARATION OF MEDICINES FOR TREATING A VARIETY OF INTRACTABLE DISORDERS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1996/009044 International Application No.: PCT/US1994/010771
Publication Date: 28.03.1996 International Filing Date: 22.09.1994
Chapter 2 Demand Filed: 19.04.1996
IPC:
A61K 31/485 (2006.01) ,A61K 31/49 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
47
Quinolines; Isoquinolines
485
Morphinan derivatives, e.g. morphine, codeine
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
47
Quinolines; Isoquinolines
49
Cinchonan derivatives, e.g. quinine
Applicants:
SMITH, Richard, Alan [US/US]; US
LICHT, Jonathan, M. [US/US]; US
Inventors:
SMITH, Richard, Alan; US
LICHT, Jonathan, M.; US
Agent:
CAMPBELL, Cathryn ; Campbell & Flores Suite 700 4370 La Jolla Village Drive San Diego, CA 92122, US
Priority Data:
Title (EN) COMPOSITIONS USEFUL FOR THE PREPARATION OF MEDICINES FOR TREATING A VARIETY OF INTRACTABLE DISORDERS
(FR) COMPOSITIONS UTILES A LA PREPARATION DE MEDICAMENTS DESTINES AU TRAITEMENT DE DIVERS TROUBLES REFRACTAIRES
Abstract:
(EN) The present invention relates to pharmacology and provides for the use of certain compositions in the preparation of medicaments for the treatment of a variety of intractable disorders. These compositions are a combination of dextromethorphan and an inhibitor of the liver enzyme debrisoquin hydroxylase. This combination of compositions has proven successful in the treatment of intractable coughing, dermatitis, chronic pain, and tinnitus.
(FR) L'invention porte sur la pharmacologie et notamment sur l'utilisation de certaines compositions dans la préparation de médicaments destinés au traitement de divers troubles réfractaires. Ces compositions sont une association de dextrométhorphane et d'un inhibiteur de l'enzyme hépatique débrisoquine hydroxylase. Cette association de compositions s'avère fructueuse dans le traitement de la toux rebelle, l'eczéma, les douleurs chroniques et l'acouphène.
Designated States: AM, AU, BB, BG, BR, BY, CA, CN, CZ, FI, GE, HU, JP, KE, KP, KR, KZ, LK, LV, MG, MN, MW, NO, NZ, PL, RO, RU, SD, SK, UA, US, UZ, VN
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP0788359EP1634597US5863927USRE038115JPH10505864 DE000069434794
AU1994080718