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1. (WO1996008272) USE OF ANTIBODIES TO BLOCK THE EFFECTS OF GRAM-POSITIVE BACTERIA AND MYCOBACTERIA
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1996/008272    International Application No.:    PCT/US1995/011770
Publication Date: 21.03.1996 International Filing Date: 15.09.1995
Chapter 2 Demand Filed:    04.04.1996    
IPC:
A61K 38/00 (2006.01), C07K 16/24 (2006.01), C07K 16/28 (2006.01)
Applicants: THE SCRIPPS RESEARCH INSTITUTE [US/US]; 10666 North Torrey Pines Road, La Jolla, Ca 92037 (US)
Inventors: ULEVITCH, Richard, J.; (US).
TOBIAS, Peter, S.; (US).
PUGIN, Jerome; (CH)
Agent: LEARN, June, M.; Fish & Richardson P.C., Suite 1400, 4225 Executive Square, La Jolla, CA 92037 (US)
Priority Data:
08/307,931 16.09.1994 US
Title (EN) USE OF ANTIBODIES TO BLOCK THE EFFECTS OF GRAM-POSITIVE BACTERIA AND MYCOBACTERIA
(FR) UTILISATION D'ANTICORPS POUR BLOQUER LES EFFETS DES BACTERIES GRAM-POSITIVES ET DES MYCOBACTERIES
Abstract: front page image
(EN)The present invention concerns a method of treating bacteremia, sepsis and other forms of toxemia caused by Gram-positive bacteria and mycobacteria comprising administering a therapeutically effective amount of anti-CD14 antibody molecules. A therapeutic composition comprising anti-CD14 antibody molecules in a pharmaceutically acceptable excipient is also contemplated.
(FR)L'invention porte sur une méthode de traitement de la bactériémie, de la septicémie et autres formes de toxémie causées par des bactéries Gram-positives et des mycobactéries, consistant à administrer une dose efficace de molécules de l'anticorps anti-CD14. L'invention porte également sur des molécules de l'anticorps anti-CD14 placées dans un excipient pharmacocompatible.
Designated States: AM, AT, AU, BB, BG, BR, BY, CA, CH, CN, CZ, DE, DK, EE, ES, FI, GB, GE, HU, IS, JP, KE, KG, KP, KR, KZ, LK, LR, LT, LU, LV, MD, MG, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, TJ, TM, TT, UA, UG, UZ, VN.
African Regional Intellectual Property Organization (KE, MW, SD, SZ, UG)
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)