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1. WO1996007629 - TECHNETIUM CHELATES TO BE USED FOR DETERMINING THE RENAL FUNCTION

Publication Number WO/1996/007629
Publication Date 14.03.1996
International Application No. PCT/US1995/011334
International Filing Date 07.09.1995
Chapter 2 Demand Filed 05.04.1996
IPC
C07F 13/00 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
FACYCLIC, CARBOCYCLIC, OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
13Compounds containing elements of Groups 7 or 17 of the Periodic System
C07K 5/083 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
5Peptides having up to four amino acids in a fully defined sequence; Derivatives thereof
04containing only normal peptide links
08Tripeptides
083the side chain of the first amino acid being acyclic, e.g. Gly, Ala
CPC
C07F 13/005
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
13Compounds containing elements of Groups 7 or 17 of the Periodic System
005Compounds without a metal-carbon linkage
C07K 5/0806
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
5Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
04containing only normal peptide links
08Tripeptides
0802with the first amino acid being neutral
0804and aliphatic
0806the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
Applicants
  • MALLINCKRODT MEDICAL, INC. [US]/[US] (AllExceptUS)
  • VERBRUGGEN, Alfons, M. [BE]/[BE] (UsOnly)
Inventors
  • VERBRUGGEN, Alfons, M.
Agents
  • MCBRIDE, Thomas, P.
Priority Data
94202574.308.09.1994EP
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) TECHNETIUM CHELATES TO BE USED FOR DETERMINING THE RENAL FUNCTION
(FR) CHELATES AU TECHNETIUM UTILISES POUR EVALUER LA FONCTION RENALE
Abstract
(EN)
The invention relates to a compound of general formula (I) wherein: Y is a thio function or a group of formula (a), Z is a carboxy group, a (C1-C4)alkoxycarbonyl group, an aminocarbonyl group, an aminosulphonyl group or a carboxymethylaminocarbonyl group; and Tc represents technetium-99 m. The invention further relates to a new chelating agent and to a kit suitable for preparing a radiopharmaceutical preparation.
(FR)
L'invention concerne un composé de la formule générale (I) dans laquelle Y représente une fonction thio ou un groupe de la formule (a), Z représente un groupe carboxy, un groupe (C1-C4)alcoxycarbonyle, un groupe aminocarbonyle, un groupe aminosulfuryle ou un groupe carboxyméthylaminocarbonyle, et Tc représente le technetium-99m. L'invention concerne également un nouvel agent chelateur ainsi qu'un matériel destiné à la confection d'une préparation radiopharmaceutique.
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