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Machine translation
1. (WO1996007405) EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1996/007405    International Application No.:    PCT/US1995/010031
Publication Date: 14.03.1996 International Filing Date: 07.08.1995
Chapter 2 Demand Filed:    29.02.1996    
IPC:
C07C 62/12 (2006.01), C07C 62/18 (2006.01), C07C 62/22 (2006.01), C07C 62/26 (2006.01), C07D 211/34 (2006.01), C07D 233/76 (2006.01), C07D 311/80 (2006.01)
Applicants: ELI LILLY AND COMPANY [US/US]; Lilly Corporate Center, Indianapolis, IN 46285 (US) (For All Designated States Except US).
ARNOLD, Macklin, Brian [US/US]; (US) (For US Only).
BLEISCH, Thomas, J. [US/US]; (US) (For US Only).
HELTON, David, Reed [US/US]; (US) (For US Only).
KALLMAN, Mary, Jeanne [US/US]; (US) (For US Only).
ORNSTEIN, Paul, Leslie [US/US]; (US) (For US Only).
SCHOEPP, Darryle, Darwin [US/US]; (US) (For US Only).
TIZZANO, Joseph, Patrick [US/US]; (US) (For US Only)
Inventors: ARNOLD, Macklin, Brian; (US).
BLEISCH, Thomas, J.; (US).
HELTON, David, Reed; (US).
KALLMAN, Mary, Jeanne; (US).
ORNSTEIN, Paul, Leslie; (US).
SCHOEPP, Darryle, Darwin; (US).
TIZZANO, Joseph, Patrick; (US)
Agent: LAMMERT, Steven, R.; Barnes & Thornburg, 1313 Merchants Bank Building, 11 South Meridian Street, Indianapolis, IN 46204 (US)
Priority Data:
08/303,255 08.09.1994 US
08/500,303 10.07.1995 US
Title (EN) EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS
(FR) ANTAGONISTES DES RECEPTEURS D'ACIDES AMINES EXCITATEURS
Abstract: front page image
(EN)The present invention provides compounds of formula (I) in which R is as defined in the specification, or a pharmaceutically acceptable metabolically labile ester or amide thereof, or a pharmaceutically acceptable salt thereof, which are useful as antagonists of one or more of the actions of L-glutamate at metabotropic excitatory amino acid receptors.
(FR)Cette invention concerne des composés de formule (I), dans laquelle R est tel que défini dans le descriptif, ou un ester ou amide pharmaceutiquement acceptable de ces composés qui est métaboliquement labile, ou encore un sel pharmaceutiquement acceptable de ces composés, qu'on utilise comme antagonistes d'une ou de plusieurs actions du L-glutamate au niveau des récepteurs d'acides aminés excitateurs métabotropiques.
Designated States: AM, AT, AU, BB, BG, BR, BY, CA, CH, CN, CZ, DE, DK, EE, ES, FI, GB, GE, HU, IS, JP, KE, KG, KP, KR, KZ, LK, LR, LT, LU, LV, MD, MG, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, TJ, TM, TT, UA, UG, US, UZ, VN.
African Regional Intellectual Property Organization (KE, MW, SD, SZ, UG)
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)