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Machine translation
1. (WO1996006867) METHOD FOR CONTROLLING O-DESULFATION OF HEPARIN AND COMPOSITIONS PRODUCED THEREBY
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1996/006867    International Application No.:    PCT/US1995/011174
Publication Date: 07.03.1996 International Filing Date: 01.09.1995
Chapter 2 Demand Filed:    12.03.1996    
IPC:
A61K 31/727 (2006.01), C08B 37/00 (2006.01)
Applicants: GLYCOMED INCORPORATED [US/US]; 860 Atlantic Avenue, Alameda, CA 94501 (US)
Inventors: HOLME, Kevin, R.; (US).
LIANG, Weisheng; (US).
TYRRELL, David, J.; (US).
SHAKLEE, Patrick, N.; (US)
Agent: WOLFF, Jessica, R.; Lyon & Lyon, First Interstate World Center, Suite 4700, 633 West Fifth Street, Los Angeles, CA 90071-2066 (US).
VIERING, JENTSCHURA & PARTNER; Steinsdorfstrasse 6, D-80538 München (DE)
Priority Data:
08/300,291 01.09.1994 US
08/384,298 06.02.1995 US
Title (EN) METHOD FOR CONTROLLING O-DESULFATION OF HEPARIN AND COMPOSITIONS PRODUCED THEREBY
(FR) METHODE DE REGULATION DE LA O-DESULFATATION DE L'HEPARINE ET DES COMPOSITIONS QUI EN DECOULENT
Abstract: front page image
(EN)Methods of making and using, as prophylactics or therapeutics for preventing or treating certain diseases including cancer, O-desulfated heparin compositions, preferably 2-O, 3-O desulfated heparin compositions, wherein the methods permit regulating the degree of 2-O, 3-O desulfation to produce compositions that are variably desulfated up to about 99 % and 75 % desulfated at the 2-O and 3-O positions, respectively.
(FR)Il s'agit de méthodes destinées à produire et à utiliser des compositions d'héparine O-désulfatées, de préférence des compositions d'héparine 2-O et 3-O désulfatées, comme agents prophylactiques ou thérapeutiques pour la prévention ou le traitement de certaines maladies, y compris le cancer. Ces méthodes permettent de réguler le degré de 2-O et 3-O de désulfatation afin de produire des compositions qui sont désulfatées de manière variable, dans des proportions allant de, respectivement, 99 et 75 % de désulfatation aux positions 2-O et 3-O.
Designated States: AM, AT, AU, BB, BG, BR, BY, CA, CH, CN, CZ, DE, DK, EE, ES, FI, GB, GE, HU, IS, JP, KE, KG, KP, KR, KZ, LK, LR, LT, LU, LV, MD, MG, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, TJ, TM, TT, UA, UG, UZ, VN.
African Regional Intellectual Property Organization (KE, MW, SD, SZ, UG)
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)