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Machine translation
1. (WO1996006609) INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1996/006609    International Application No.:    PCT/US1995/010827
Publication Date: 07.03.1996 International Filing Date: 25.08.1995
Chapter 2 Demand Filed:    18.03.1996    
IPC:
A61K 31/445 (2006.01), A61K 31/4468 (2006.01), A61K 31/4545 (2006.01), C07D 211/22 (2006.01), C07D 211/32 (2006.01), C07D 211/34 (2006.01), C07D 211/48 (2006.01), C07D 211/54 (2006.01), C07D 211/64 (2006.01)
Applicants: MERCK & CO., INC. [US/US]; 126 East Lincoln Avenue, Rahway, NJ 07065 (US) (For All Designated States Except US).
FISHER, Thorsten, E. [US/US]; (US) (For US Only).
WAI, John, S. [GB/US]; (US) (For US Only).
CULBERSON, J., Christopher [US/US]; (US) (For US Only).
SAARI, Walfred, S. [US/US]; (US) (For US Only)
Inventors: FISHER, Thorsten, E.; (US).
WAI, John, S.; (US).
CULBERSON, J., Christopher; (US).
SAARI, Walfred, S.; (US)
Common
Representative:
MERCK & CO., INC.; 126 East Lincoln Avenue, Rahway, NJ 07065 (US)
Priority Data:
298,478 29.08.1994 US
Title (EN) INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE
(FR) INHIBITEURS DE LA FARNESYLE-PROTEINE TRANSFERASE
Abstract: front page image
(EN)The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and treatment of cancer.
(FR)L'invention concerne des composés qui inhibent la farnésyle-protéine transférase (FTase) et la farnésylation de la protéine encogène Ras. L'invention concerne également des compositions contenant lesdits composés, utilisées en chimiothérapie, ainsi que des procédés d'inhibition de la farnésyle-protéine transférase et de traitement du cancer.
Designated States: AM, AU, BB, BG, BR, BY, CA, CN, CZ, EE, FI, GE, HU, IS, JP, KG, KR, KZ, LK, LR, LT, LV, MD, MG, MK, MN, MX, NO, NZ, PL, RO, RU, SG, SI, SK, TJ, TM, TT, UA, US, UZ.
African Regional Intellectual Property Organization (KE, MW, SD, SZ, UG)
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)