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1. WO1996006604 - METHODS FOR IDENTIFYING AND TREATING RESISTANT TUMORS

Publication Number WO/1996/006604
Publication Date 07.03.1996
International Application No. PCT/US1995/011125
International Filing Date 31.08.1995
Chapter 2 Demand Filed 29.03.1996
IPC
A61K 31/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
A61K 31/192 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
19Carboxylic acids, e.g. valproic acid
192having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
A61K 31/353 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
335having oxygen as the only ring hetero atom, e.g. fungichromin
35having six-membered rings with one oxygen as the only ring hetero atom
352condensed with carbocyclic rings, e.g. cannabinols, methantheline
3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
A61K 31/47 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
47Quinolines; Isoquinolines
CPC
A61K 31/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
A61K 31/192
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic, hydroximic acids
19Carboxylic acids, e.g. valproic acid
192having aromatic groups, e.g. sulindac, 2-arylpropionic acids, ethacrynic acid
A61K 31/353
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
335having oxygen as the only ring hetero atom, e.g. fungichromin
35having six-membered rings with one oxygen as the only ring hetero atom
352condensed with carbocyclic rings, e.g. cannabinols, methantheline
3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
A61K 31/47
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
47Quinolines; Isoquinolines
A61P 43/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Applicants
  • ELI LILLY AND COMPANY [US]/[US] (AllExceptUS)
  • DEUTSCHES KREBSFORSCHUNGSZENTRUM [DE]/[DE] (AllExceptUS)
  • SAWYER, Jason, Scott [US]/[US] (UsOnly)
  • SPAETHE, Stephen, M. [US]/[US] (UsOnly)
  • STARLING, James, Jacob [US]/[US] (UsOnly)
  • JEDLITSCHKY, Gabriele [DE]/[DE] (UsOnly)
  • LEIER, Inka [DE]/[DE] (UsOnly)
  • KEPPLER, Dietrich [DE]/[DE] (UsOnly)
Inventors
  • SAWYER, Jason, Scott
  • SPAETHE, Stephen, M.
  • STARLING, James, Jacob
  • JEDLITSCHKY, Gabriele
  • LEIER, Inka
  • KEPPLER, Dietrich
Agents
  • LAMMERT, Steven, R.
  • HUBER, Bernard
Priority Data
08/298,64431.08.1994US
P 44 32 563.013.09.1994DE
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHODS FOR IDENTIFYING AND TREATING RESISTANT TUMORS
(FR) PROCEDES D'IDENTIFICATION ET DE TRAITEMENT DE TUMEURS RESISTANTES
Abstract
(EN)
This invention provides a method of identifying and reversing multidrug resistance in a multidrug resistance tumor comprising administering a multidrug resistance reversing amount of any of the compounds as defined herein.
(FR)
L'invention concerne un procédé d'identification et d'inversion de la résistance multiple aux anticancéreux d'une tumeur, qui consiste à administrer une certaine quantité de n'importe lequel des composés définis dans cette invention, cette quantité étant suffisante pour réaliser l'inversion de la résistance multiple aux anticancéreux.
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