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Machine translation
1. (WO1996006113) NEW IMMUNOCONTRACEPTIVE PEPTIDES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1996/006113    International Application No.:    PCT/EP1995/003311
Publication Date: 29.02.1996 International Filing Date: 18.08.1995
Chapter 2 Demand Filed:    29.01.1996    
IPC:
A61K 39/00 (2006.01), C07K 14/705 (2006.01)
Applicants: AKZO NOBEL N.V. [NL/NL]; Velperweg 76, NL-6824 BM Arnhem (NL) (For All Designated States Except US).
VAN DUIN, Marcel [NL/NL]; (NL) (For US Only).
GROOTENHUIS, Arij, Jan [NL/NL]; (NL) (For US Only).
BUNSCHOTEN, Evert, Johannes [NL/NL]; (NL) (For US Only)
Inventors: VAN DUIN, Marcel; (NL).
GROOTENHUIS, Arij, Jan; (NL).
BUNSCHOTEN, Evert, Johannes; (NL)
Agent: BEETZ, T.; Postbus 20, NL-5340 BH Oss (NL)
Priority Data:
94202392.0 22.08.1994 EP
Title (EN) NEW IMMUNOCONTRACEPTIVE PEPTIDES
(FR) NOUVEAUX PEPTIDES IMMUNO-CONTRACEPTIFS
Abstract: front page image
(EN)The present invention relates to a peptide capable of inducing an immune response against the Zona Pellucida protein ZP3, said peptide having an amino acid sequence of 8-50 amino acid residues and comprising at least the amino acid sequence PLWLLQ or analogues thereof. More specifically, the peptides according to the invention comprise at least the amino acid sequence QPLWLLQG. Further embodiments of the invention relate to antibodies raised against the peptides according to the invention, contraceptive vaccines comprising said peptides or said antibodies, as well as a test kit for the detection of autoimmune antibodies against ZP3 in a test sample.
(FR)L'invention concerne un peptide susceptible d'induire une réponse immune contre la protéine ZP3 de la zone pellucide, ce peptide possédant une séquence d'acides aminés comprenant 8 à 50 restes d'acides aminés ainsi qu'au moins la séquence PLWLLQ ou des analogues de celle-ci. Plus particulièrement, les peptides selon l'invention comprennent au moins la séquence d'acides aminés QPLWLLQG. On décrit encore des anticorps dirigés contre les peptides selon l'invention, des vaccins contraceptifs comprenant ces peptides ou ces anticorps, ainsi qu'un nécessaire d'essai destiné à la détection des anticorps auto-immuns dirigés contre la protéine ZP3 dans un échantillon d'essai.
Designated States: AM, AU, BB, BG, BR, BY, CA, CN, CZ, EE, FI, GE, HU, JP, KE, KG, KP, KR, KZ, LK, LR, LT, LV, MD, MG, MN, MW, MX, NO, NZ, PL, RO, RU, SD, SI, SK, TJ, TT, UA, US, UZ, VN.
African Regional Intellectual Property Organization (KE, MW, SD, SZ, UG)
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)