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1. WO1996006101 - AMINO ACID CHELATES HAVING IMPROVED PALATABILITY

Publication Number WO/1996/006101
Publication Date 29.02.1996
International Application No. PCT/US1995/010568
International Filing Date 21.08.1995
Chapter 2 Demand Filed 05.02.1996
IPC
C07C 229/76 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
229Compounds containing amino and carboxyl groups bound to the same carbon skeleton
76Metal complexes of amino carboxylic acids
C07F 1/00 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
FACYCLIC, CARBOCYCLIC, OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
1Compounds containing elements of Groups 1 or 11 of the Periodic System
C07F 3/00 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
FACYCLIC, CARBOCYCLIC, OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
3Compounds containing elements of Groups 2 or 12 of the Periodic System
C07F 11/00 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
FACYCLIC, CARBOCYCLIC, OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
11Compounds containing elements of Groups 6 or 16 of the Periodic System
C07F 13/00 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
FACYCLIC, CARBOCYCLIC, OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
13Compounds containing elements of Groups 7 or 17 of the Periodic System
C07F 15/02 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
FACYCLIC, CARBOCYCLIC, OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
15Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System
02Iron compounds
CPC
C07C 229/76
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
229Compounds containing amino and carboxyl groups bound to the same carbon skeleton
76Metal complexes of amino carboxylic acids
C07F 1/005
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
1Compounds containing elements of Groups 1 or 11 of the Periodic System
005without C-Metal linkages
C07F 11/005
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
11Compounds containing elements of Groups 6 or 16 of the Periodic System
005compounds without a metal-carbon linkage
C07F 13/005
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
13Compounds containing elements of Groups 7 or 17 of the Periodic System
005Compounds without a metal-carbon linkage
C07F 15/025
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
15Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System
02Iron compounds
025without a metal-carbon linkage
C07F 15/065
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
15Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System
06Cobalt compounds
065without a metal-carbon linkage
Applicants
  • ALBION INTERNATIONAL, INC. [US/US]; 101 North Main Clearfield, UT 84015, US
Inventors
  • PEDERSEN, Mark; US
  • ASHMEAD, H., DeWayne; US
Agents
  • WESTERN, M., Wayne ; Thorpe, North & Western Suite 200 9035 South 700 East Sandy, UT 84070, US
Priority Data
08/294,63223.08.1994US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) AMINO ACID CHELATES HAVING IMPROVED PALATABILITY
(FR) COMPLEXES D'ACIDES AMINES AYANT UN GOUT AMELIORE
Abstract
(EN)
A palatable metal amino acid chelate for administration to humans and other warm-blooded animals is disclosed wherein there are sufficient ligands to provide ionic and coordinate covalent bonds equal to the coordination number of the central metal ion while, at the same time, maintaining charge balance in the chelate molecule. There must be at least one ligand of the polydentate type which must be an $g(a)-amino acid with the further proviso that any unidentate or polydentate ligand(s) must be charge balanced organic ligands. Charge balancing may be accomplished by means of an organic acid and dicarboxylic, hydroxycarboxylic, hydroxydicarboxylic or hydroxytricarboxylic acids in particular, which maintains the chelate molecule as an optimum pH for purposes of stability and palatability.
(FR)
On décrit des complexes d'acides aminés et de métaux ayant un goût amélioré pour une administration à des humains et à des animaux à sang chaud, comprenant suffisamment de ligands pour assurer des liaisons ioniques et des liaisons covalentes de coordination, en un nombre égal au nombre de coordination de l'ion métallique central, tout en assurant en même temps l'équilibre des charges à l'intérieur de la molécule de complexe. Il doit y avoir au moins un ligand du type polydentate qui doit être un acide $g(a)-aminé et tout ligand monodentate ou polydentate doit être un ligand organique équilibré du point de vue des charges. L'équilibre des charges peut être obtenu au moyen d'un acide organique tel qu'en particulier un acide dicarboxylique, un acide hydroxycarboxylique, un acide hydroxydicarboxylique ou un acide hydroxytricarboxylique, qui maintient la molécule de complexe à un pH optimum pour la stabilité et le goût.
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