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1. WO1996005836 - METHODS OF TREATING COLD SYMPTOMS USING PENTOXIFYLLINE

Publication Number WO/1996/005836
Publication Date 29.02.1996
International Application No. PCT/US1995/010840
International Filing Date 25.08.1995
Chapter 2 Demand Filed 25.03.1996
IPC
A61K 31/52 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
519ortho- or peri-condensed with heterocyclic rings
52Purines, e.g. adenine
CPC
A61K 31/522
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495having six-membered rings with two ; or more; nitrogen atoms as the only ring heteroatoms, e.g. piperazine ; or tetrazines
505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
519ortho- or peri-condensed with heterocyclic rings
52Purines, e.g. adenine
522having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
Applicants
  • MEDICAL UNIVERSITY OF SOUTH CAROLINA [US/US]; 171 Ashley Avenue Charleston, SC 29425, US
Inventors
  • TURNER, Ronald, B.; US
Agents
  • NEEDLE, William, H. ; Needle & Rosenberg, P.C. Suite 1200 127 Peachtree Street, N.W. Atlanta, GA 30303-1811, US
  • SARUP, David Alexander; Withers & Rogers 4 Dyer's Buildings Holborn London EC1N 2JT, GB
Priority Data
08/296,48725.08.1994US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHODS OF TREATING COLD SYMPTOMS USING PENTOXIFYLLINE
(FR) PROCEDES DE TRAITEMENT DE SYMPTOMES DUS AU FROID AU MOYEN DE LA PENTOXIFYLLINE
Abstract
(EN)
The invention provides a method of alleviating a symptom of an upper respiratory viral infection in a subject, comprising administering to the subject an effective amount of pentoxifylline or an analog thereof. The invention also provides a method of inhibiting interleukin-8 elaboration in a subject comprising administering to the subject an effective amount of pentoxifylline or an analog thereof. A pharmaceutical composition for alleviating a symptom of an upper respiratory viral infection is also provided, comprising an effective amount of pentoxifylline or an analog thereof in a pharmaceutically acceptable nasal spray carrier.
(FR)
L'invention se rapporte à un procédé permettant d'atténuer un symptôme d'une infection virale des voies respiratoires supérieures chez un sujet, ce procédé consistant à administrer au sujet une dose efficace de pentoxifylline ou d'un analogue de celle-ci. L'invention se rapporte également à un procédé d'inhibition de la production de l'interleukine 8 chez un sujet, procédé consistant à administrer au sujet une dose efficace de pentoxyfylline ou d'un analogue de celle-ci. L'invention concerne en outre une composition pharmaceutique destinée à atténuer un symptôme d'une infection virale des voies respiratoires supérieures, et comprenant une dose efficace de pentoxifylline ou d'un analogue de celle-ci dans un excipient pharmaceutiquement acceptable s'appliquant par pulvérisation nasales.
Also published as
Latest bibliographic data on file with the International Bureau