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1. WO1996005835 - USE OF ZAPRINAST FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF ACUTE RENAL FAILURE

Publication Number WO/1996/005835
Publication Date 29.02.1996
International Application No. PCT/US1995/010148
International Filing Date 21.08.1995
Chapter 2 Demand Filed 04.03.1996
IPC
A61K 31/519 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
519ortho- or peri-condensed with heterocyclic rings
CPC
A61K 31/519
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495having six-membered rings with two ; or more; nitrogen atoms as the only ring heteroatoms, e.g. piperazine ; or tetrazines
505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
519ortho- or peri-condensed with heterocyclic rings
A61P 13/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
13Drugs for disorders of the urinary system
02of urine or of the urinary tract, e.g. urine acidifiers
A61P 15/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
15Drugs for genital or sexual disorders
Applicants
  • WASHINGTON UNIVERSITY [US/US]; One Brookings Drive St. Louis, MO 63130, US (AllExceptUS)
  • GREENWALD, James, E. [US/US]; US (UsOnly)
Inventors
  • GREENWALD, James, E.; US
Agents
  • MEYER, Scott, J. ; G.D. Searle & Co. Corporate Patent Dept. P.O. Box 5110 Chicago, IL 60680-5110, US
  • BEIL, Hans, Chr.; Adelonstrasse 58 Postfach 80 01 40 D-65901 Frankfurt-am-Main 80, DE
Priority Data
08/293,98922.08.1994US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) USE OF ZAPRINAST FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF ACUTE RENAL FAILURE
(FR) UTILISATION DE ZAPRINAST POUR LA PREPARATION D'UN MEDICAMENT DESTINE AU TRAITEMENT DE L'INSUFFISANCE RENALE AIGUE
Abstract
(EN)
A method is disclosed for treatment of acute renal failure which comprises administering to a warm-blooded mammal manifesting acute renal failure a small but effective amount of zaprinast sufficient to effect acceleration of recovery from said acute renal failure.
(FR)
Méthode de traitement de l'insuffisance rénale aiguë consistant à administrer à un mammifère à sang chaud atteint d'une telle insuffisance, une dose faible mais efficace de zaprinast suffisante pour accélérer la guérison.
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