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1. WO1996005834 - IMPROVED PHARMACEUTICAL FORMULATIONS CONTAINING IBUPROFEN AND CODEINE

Publication Number WO/1996/005834
Publication Date 29.02.1996
International Application No. PCT/GB1995/001947
International Filing Date 16.08.1995
Chapter 2 Demand Filed 14.03.1996
IPC
A61K 9/20 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
20Pills, lozenges or tablets
A61K 31/485 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
47Quinolines; Isoquinolines
485Morphinan derivatives, e.g. morphine, codeine
CPC
A61K 31/485
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
47Quinolines; Isoquinolines
485Morphinan derivatives, e.g. morphine, codeine
A61K 9/2018
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
20Pills, tablets, ; discs, rods
2004Excipients; Inactive ingredients
2013Organic compounds, e.g. phospholipids, fats
2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
A61K 9/2054
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
20Pills, tablets, ; discs, rods
2004Excipients; Inactive ingredients
2022Organic macromolecular compounds
205Polysaccharides, e.g. alginate, gums; Cyclodextrin
2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
Applicants
  • SMITHKLINE BEECHAM PLC [GB]/[GB]
Inventors
  • HOLMES, Brian
Agents
  • SANDERSON & CO.
Priority Data
9417041.223.08.1994GB
9419921.304.10.1994GB
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) IMPROVED PHARMACEUTICAL FORMULATIONS CONTAINING IBUPROFEN AND CODEINE
(FR) FORMULATIONS PHARMACEUTIQUES AMELIOREES CONTENANT DE L'IBUPROFENE ET DE LA CODEINE
Abstract
(EN)
Formulations of ibuprofen and codeine (or a pharmaceutically acceptable salt of either of them) include a carrier comprising a disintegrant, diluent, and a lubricant substantially free from stearic acid and stearate ions and selected from hydrogenated vegetable oils. Preferred formulations are directly-compressed tablets which are useful for treating pain and inflammation.
(FR)
Formulations d'ibuprofène et de codéine (ou un sel pharmacologiquement acceptable de l'une ou l'autre) comprenant un vecteur contenant un agent de désintégration, un diluant et un lubrifiant pratiquement dépourvus d'acide stéarique et d'ions stéarate et choisis parmi des huiles végétales hydrogénées. Des cachets directement comprimés, utiles pour traiter des douleurs et des inflammations, constituent les formulations préférées.
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