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1. WO1996005814 - OESTRADIOL TRANSDERMAL THERAPEUTIC SYSTEM COMPRISING HYGROSCOPIC ADDITIVES

Publication Number WO/1996/005814
Publication Date 29.02.1996
International Application No. PCT/EP1995/003201
International Filing Date 12.08.1995
Chapter 2 Demand Filed 14.03.1996
IPC
A61K 9/70 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
70Web, sheet or filament bases
CPC
A61K 9/7053
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
70Web, sheet or filament bases ; ; Films; Fibres of the matrix type containing drug;
7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
703characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
7046the adhesive comprising macromolecular compounds
7053obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
A61K 9/7069
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
70Web, sheet or filament bases ; ; Films; Fibres of the matrix type containing drug;
7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
703characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
7046the adhesive comprising macromolecular compounds
7069obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
A61P 15/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
15Drugs for genital or sexual disorders
12for climacteric disorders
A61P 19/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
19Drugs for skeletal disorders
08for bone diseases, e.g. rachitism, Paget's disease
10for osteoporosis
Y10S 514/943
YSECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
10TECHNICAL SUBJECTS COVERED BY FORMER USPC
STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
514Drug, bio-affecting and body treating compositions
937Dispersion or emulsion
938Oil-water type
939Mineral oil-water type
943Higher fatty acid or derivative containing
Y10S 514/946
YSECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
10TECHNICAL SUBJECTS COVERED BY FORMER USPC
STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
514Drug, bio-affecting and body treating compositions
946Penetrant or absorbent, increases or enhances penetration into subject treated
Applicants
  • LTS LOHMANN THERAPIE-SYSTEME GMBH [DE/DE]; Irlicher Strasse 55 D-56567 Neuwied, DE (AllExceptUS)
  • MÜLLER, Walter [DE/DE]; DE (UsOnly)
  • HORSTMANN, Michael [DE/DE]; DE (UsOnly)
Inventors
  • MÜLLER, Walter; DE
  • HORSTMANN, Michael; DE
Agents
  • FLACCUS, Rolf-Dieter; Sperlingsweg 32 D-50389 Wesseling, DE
Priority Data
P 44 29 667.320.08.1994DE
Publication Language German (DE)
Filing Language German (DE)
Designated States
Title
(DE) ESTRADIOL-TTS MIT WASSERBINDENDEN ZUSÄTZEN
(EN) OESTRADIOL TRANSDERMAL THERAPEUTIC SYSTEM COMPRISING HYGROSCOPIC ADDITIVES
(FR) SYSTEME THERAPEUTIQUE TRANSDERMIQUE CONTENANT DE L'×STRADIOL AVEC DES ADDITIFS HYDROPHILES
Abstract
(DE)
Ein transdermales therapeutisches System, enthaltend den Wirkstoff Estradiol, mit geschichtetem Aufbau einer wirkstoff- und feuchtigkeitsundurchlässigen Rückschicht, einer wirkstoffhaltigen Matrix und fallweise einer ablösbaren, die Matrix abdeckenen Schutzschicht, ist dadurch gekennzeichnet, daß die Matrix Glycerin enthält, das maximal 1 Gew.-% Wasser enthält bzw. im wesentlichen frei von Wasser ist.
(EN)
The invention concerns a transdermal therapeutic system which contains oestradiol as active substance and has a layered structure. This layered structure comprises a backing which is impervious to the active substance and moisture, an active substance-containing matrix and, possibly, a separable protective layer covering the matrix. The system is characterized in that the matrix contains glycerol which contains a maximum of 1 % water or which is substantially anhydrous.
(FR)
L'invention concerne un système thérapeutique transdermique contenant de l'÷stradiol comme principe actif et comprenant plusieurs couches: une couche dorsale imperméable au principe actif et à l'humidité, une couche de matrice renfermant le principe actif et, le cas échéant, une couche de protection détachable recouvrant la matrice. L'invention se caractérise en ce que la matrice renferme de la glycérine contenant au maximum 1 % en poids d'eau ou pratiquement sans eau.
Also published as
CZPV1997-509
FI970701
NO19970360
NZ291813
SK199700220
SK22097
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