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1. WO1996005812 - HYDROPHILIC CONTROLLED RELEASE DEVICE

Publication Number WO/1996/005812
Publication Date 29.02.1996
International Application No. PCT/GB1995/001962
International Filing Date 18.08.1995
Chapter 2 Demand Filed 19.03.1996
IPC
A61J 3/07 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
3Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
07into the form of capsules or similar small containers for oral use
A61K 9/48 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
48Preparations in capsules, e.g. of gelatin, of chocolate
A61M 31/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
31Devices for introducing or retaining media, e.g. remedies, in cavities of the body
CPC
A61J 3/071
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
3Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
07into the form of capsules or similar small containers for oral use
071into the form of telescopically engaged two-piece capsules
A61K 9/4808
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
48Preparations in capsules, e.g. of gelatin, of chocolate
4808characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
A61M 31/002
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
31Devices for introducing or retaining media, e.g. remedies, in cavities of the body
002Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
Applicants
  • R.P. SCHERER CORPORATION [US/US]; 2075 West Big Beaver Road Troy, MI 48084, US (AllExceptUS)
  • MACLEOD, Graeme, Scott [GB/GB]; GB (UsOnly)
  • MILLER, Christopher, Jon [GB/GB]; GB (UsOnly)
  • MACRAE, David, Kean [GB/GB]; GB (UsOnly)
  • STEVENS, Howard, Norman, Ernest [GB/GB]; GB (UsOnly)
  • HEGARTY, Mark [GB/GB]; GB (UsOnly)
Inventors
  • MACLEOD, Graeme, Scott; GB
  • MILLER, Christopher, Jon; GB
  • MACRAE, David, Kean; GB
  • STEVENS, Howard, Norman, Ernest; GB
  • HEGARTY, Mark; GB
Agents
  • McCALLUM, William, Potter ; Cruikshank & Fairweather 19 Royal Exchange Square Glasgow G1 3AE, GB
Priority Data
9416902.620.08.1994GB
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) HYDROPHILIC CONTROLLED RELEASE DEVICE
(FR) DISPOSITIF HYDROPHILE A LIBERATION MODULEE
Abstract
(EN)
A capsule body (6) for a controlled release device has a coating of a hydrophilic material at least inside the neck region (4) adjacent the opening (15). The hydrophilic material may be a film forming material and/or a surfactant. Its purpose is to facilitate ingress of water into the capsule body in order to release a pharmaceutical material contained therein, once the hydrogel plug (2) has swollen and become disengaged from the body after a predetermined time interval. A preferred hydrophilic coating is formed of a mixture of ethyl cellulose and sodium docusate.
(FR)
Un corps de capsule (6), destiné à un dispositif à libération modulée, comprend un revêtement d'un matériau hydrophile présent au moins dans la zone du col (4) adjacente à son ouverture (15). Ce matériau hydrophile peut être un matériau et/ou un agent tensioactif destiné à former une pellicule. Son objet est de faciliter la pénétration de l'eau dans le corps de capsule pour libérer une substance pharmaceutique qui y est contenue, une fois qu'un tampon d'hydrogel (2) a gonflé et s'est dégagé du corps après une durée prédéterminée. Un revêtement hydrophile préféré est constitué d'un mélange d'éthyle cellulose et de docusate de sodium.
Also published as
Latest bibliographic data on file with the International Bureau