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1. WO1996005326 - METHOD AND APPARATUS FOR MAGNETICALLY DETECTING PROTEINS AND NUCLEIC ACIDS

Publication Number WO/1996/005326
Publication Date 22.02.1996
International Application No. PCT/US1995/010503
International Filing Date 17.08.1995
Chapter 2 Demand Filed 15.03.1996
IPC
C12Q 1/68 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
G01N 33/543 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
543with an insoluble carrier for immobilising immunochemicals
G01N 33/58 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
58involving labelled substances
G01N 35/00 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
35Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/-G01N33/148; Handling materials therefor
CPC
C12Q 1/6825
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms
68involving nucleic acids
6813Hybridisation assays
6816characterised by the detection means
6825Nucleic acid detection involving sensors
G01N 33/54326
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
543with an insoluble carrier for immobilising immunochemicals
54313the carrier being characterised by its particulate form
54326Magnetic particles
G01N 33/58
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
58involving labelled substances
G01N 35/0098
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
35Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
0098involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation
Applicants
  • FOX, John, S. [US/US]; US
Inventors
  • FOX, John, S.; US
Agents
  • ROGITZ, John, L.; Rogitz & Associates Suite 3120 750 "B" Street San Diego, CA 92101, US
Priority Data
08/291,95617.08.1994US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHOD AND APPARATUS FOR MAGNETICALLY DETECTING PROTEINS AND NUCLEIC ACIDS
(FR) METHODE ET DISPOSITIF DE DETECTION MAGNETIQUE DE PROTEINES ET D'ACIDES NUCLEIQUES
Abstract
(EN)
A biochemical assay device for detecting the presence of DNA, RNA, proteins, or antibodies (14) includes a colloidal compound having a magnetic marker constituent (16) which binds to the DNA, RNA, protein, or antibody (14) sought to be detected. The DNA, RNA, protein, or antibody (14) with magnetic marker (16) is then juxtaposed with a magnetic sensor (20), and the sensor (20) generates a detection signal representative of the presence of the DNA, RNA, protein, or antibody (14). The detection signal can be correlated to a quantity of DNA, RNA, protein, or antibody (14). A method for detecting the presence of DNA, RNA, proteins, or antibodies (14) using principles of magnetism is also disclosed.
(FR)
Dispositif de titrage biochimique permettant de détecter la présence d'ARN, d'ADN, de protéines ou d'anticorps (14). Ce dispositif comprend un composé colloïdal comportant un constituant marqueur magnétique (16) qui se lie à l'ADN, à l'ARN, à la protéine ou à l'anticorps (14) que l'on souhaite détecter. L'ADN, l'ARN, la protéine ou l'anticorps (14) présentant ce marqueur magnétique (16) est ensuite juxtaposé à un capteur magnétique (20), lequel capteur (20) génère un signal de détection exprimant la présence de cet ADN, ARN, protéine ou anticorps (14). Le signal de détection peut être corrélé à une quantité donnée d'ADN, d'ARN, de protéines ou d'anticorps (14). L'invention porte également sur la méthode de détection de la présence d'ARN, d'ADN, de protéines ou d'anticorps mettant en ÷uvre les principes du magnétisme.
Also published as
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