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1. WO1996005322 - DETECTION AND TREATMENT OF BREAST CANCER

Publication Number WO/1996/005322
Publication Date 22.02.1996
International Application No. PCT/US1995/009762
International Filing Date 01.08.1995
Chapter 2 Demand Filed 04.03.1996
IPC
A61K 38/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
C07K 14/47 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
46from vertebrates
47from mammals
CPC
A61K 38/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
C07K 14/47
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
46from vertebrates
47from mammals
C07K 14/4748
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
46from vertebrates
47from mammals
4701not used
4748Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
Applicants
  • THE GENERAL HOSPITAL CORPORATION [US/US]; 55 Fruit Street Boston, MA 02114, US
  • PRESIDENT AND FELLOWS OF HARVARD COLLEGE [US/US]; 17 Quincy Street Cambridge, MA 02138, US
Inventors
  • MORRISON, Briggs, W.; US
  • LEDER, Philip; US
Agents
  • CLARK, Paul, T.; Fish & Richardson P.C. 225 Franklin Street Boston, MA 02110-2804, US
Priority Data
08/289,24711.08.1994US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) DETECTION AND TREATMENT OF BREAST CANCER
(FR) DETECTION ET TRAITEMENT DE CANCER DU SEIN
Abstract
(EN)
A novel chloride channel protein found in human breast cancer cells is disclosed. The chloride channel protein, called Mat-8, serves as a useful diagnostic reagent for the detection of breast cancer. The Mat-8 protein and chloride channel proteins generally, are useful therapeutic targets for the treatment of breast cancer.
(FR)
Cette invention concerne une nouvelle protéine du canal chlorure qu'on a trouvée dans des cellules du cancer du sein chez la femme. La protéine du canal chlorure, appelée Mat-8, sert de réactif de diagnostic utile pour détecter le cancer du sein. La protéine Mat-8 et plus généralement les protéines du canal chlorure constituent des cibles thérapeutiques utiles pour effectuer le traitement du cancer du sein.
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