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1. WO1996005312 - NOVEL TRYPANOSOMA CRUZI ANTIGEN, AND GENE CODING THEREFOR; THEIR APPLICATION TO THE DETECTION OF CHAGAS' DISEASE

Publication Number WO/1996/005312
Publication Date 22.02.1996
International Application No. PCT/FR1995/001071
International Filing Date 09.08.1995
IPC
C07K 14/44 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
44from protozoa
C12Q 1/68 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
CPC
C07K 14/44
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
44from protozoa
C12Q 1/6893
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms
68involving nucleic acids
6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
6888for detection or identification of organisms
6893for protozoa
Applicants
  • BIO MERIEUX [FR/FR]; Chemin de l'Orme F-69280 Marcy-l'Etoile, FR (AllExceptUS)
  • PARANHOS-BACCALA, Glaucia [FR/FR]; FR (UsOnly)
  • LESENECHAL, Mylène [FR/FR]; FR (UsOnly)
  • JOLIVET, Michel [FR/FR]; FR (UsOnly)
Inventors
  • PARANHOS-BACCALA, Glaucia; FR
  • LESENECHAL, Mylène; FR
  • JOLIVET, Michel; FR
Agents
  • MAUREAU, Philippe; Cabinet Germain & Maureau Boîte postale 3011 F-69392 Lyon Cédex 03, FR
Priority Data
94/1013212.08.1994FR
Publication Language French (FR)
Filing Language French (FR)
Designated States
Title
(EN) NOVEL TRYPANOSOMA CRUZI ANTIGEN, AND GENE CODING THEREFOR; THEIR APPLICATION TO THE DETECTION OF CHAGAS' DISEASE
(FR) NOUVEL ANTIGENE DE TRYPANOSOMA CRUZI, ET GENE CODANT POUR CETTE DERNIERE; LEUR APPLICATION A LA DETECTION DE LA MALADIE DE CHAGAS
Abstract
(EN)
Novel $i(Trypanosoma cruzi) antigen, known as PTc100, and a code gene, known as Tc100, coding therefor. According to the invention, Tc100 and PTc100 amino acid nucleotide sequences have been determined and described. PTc100 and Tc100 or the modified or unmodified fragments thereof, can be used directly or indirectly to detect $i(Trypanosoma cruzi) or to treat the infection caused by it in humans or animals.
(FR)
La présente invention concerne un nouvel antigène de $i(Trypanosoma cruzi), dénommé PTc100, et un gène code codant pour ce dernier, dénommé Tc100. Selon l'invention, on a déterminé et décrit les séquences nucléotidiques de Tc100 et d'acides aminés de PTc100. PTc100 et Tc100, ou leurs fragments, modifiés ou non, peuvent être utilisés directement ou indirectement pour la détection de $i(Trypanosoma cruzi), ou le suivi de l'infection générée par ce dernier, chez l'homme ou l'animal.
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